Myocardial Scintigraphy & DaTscan for Early PD Diagnosis

Condition: Parkinson's disease

Eligibility

Key Inclusion Criteria

  • Between 30 and 80 years old at time of enrollment
  • Group 1 criteria (PD): Diagnosis of idiopathic PD for at least three years
  • Group 2 criteria (Early/Pre-Motor PD): Loss of smell; rapid eye movement (REM) sleep behavioral disorder
  • Group 3 criteria (APD): Diagnosis of atypical parkinsonian variant

Key Exclusion Criteria

  • Groups 1 and 2: Presence of other diagnoses such as atypical parkinsonism
  • Family history of PD
  • Cognitive impairment
  • Severe heart disease

Full Study Name

Myocardial Scintigraphy and DaTscan for Early Diagnosis of Parkinson's Disease (IRB no. 46442)

Summary

This study focuses on patients who have symptoms that are the precursors of Parkinson’s disease (PD), PD, or types of atypical PD. The purpose of the study is to determine whether using two imaging techniques together (myocardial scintigraphy and dopamine transporter scan) is a reliable method for detecting PD early, perhaps even before someone has obvious signs of the disease. Although both imaging techniques are approved by the U.S. Food and Drug Administration for other conditions, their use is considered investigational in this study.


Principal Investigator

Echo Tan, MD