Find Clinical Trials | Cedars-Sinai

51 results found

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Lorundrostat in Uncontrolled Hypertension

The purpose of this study is to assess the blood pressure lowering effect of an experimental drug called lorundrostat (MLS 101) in combination with medications (that are approved by the U.S. Food and Drug Administration-FDA) ...

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Eplontersen in Transthyretin-Mediated Amyloid Cardiomyopathy

The purpose of this study is to evaluate the safety and effectiveness of an experimental drug called eplontersen in people with transthyretin-mediated amyloid cardiomyopathy (ATTR-CM). ATTRCM is a disease caused by change in a protein ...

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Aficamten Compared to Placebo in Symptomatic Non-Obstructive Hypertrophic Cardiomyopathy

The purpose of this study is to compare the effects of an experimental drug called aficamten and placebo (inactive substance) on the exercise capacity and health status of patients with symptomatic, non-obstructive hypertrophic cardiomyopathy (nHCM). ...

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SELUTION SLR 014 Drug Eluting Balloon in the Treatment of In-Stent Restenosis

The purpose of this study is to demonstrate whether an investigational device called the SELUTION SLR drug eluting balloon is well tolerated and whether it works as effectively as other currently available treatments for patients ...

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NIH_PREVENTABLE

The objective of PREVENTABLE is to randomly assign 20,000 adults ?75 years of age without dementia, significant disability, or clinically evident CVD in a 1:1 allocation to double-blind atorvastatin 40 mg or placebo daily and ...