The PROCEED Study

Key Inclusion Criteria

• Must be between 18-75 years old at the time of enrollment

GREEN GROUP I: No Pancreas Disease Controls

• No personal history or symptoms of pancreatic disease

GREEN GROUP II: Chronic Upper Abdominal Pain of Suspected Pancreatic Origin

• Referred to a pancreas or GI clinic or admitted to the hospital for evaluation unexplained upper abdominal pain of at least 3 months in duration

YELLOW GROUP I: Indeterminate Chronic Pancreatitis (CP) with no history of Acute Pancreatitis

• Referred to a pancreas or GI clinic or admitted to the hospital for evaluation of unexplained upper abdominal pain of at least 3 months in duration

YELLOW GROUP II: Acute Pancreatitis (AP)

• History of 1 documented attack of AP in the preceding 18 months

YELLOW GROUP III: Recurrent Acute Pancreatitis (RAP)

• 2 or more documented attacks of AP separated by at least 1 month

RED GROUP: Definite Chronic Pancreatitis

• Presence of unequivocal (definite) CP and/or parenchymal and/or ductal calcifications 

Key Exclusion Criteria

GREEN GROUP I

• History of bleeding disorders
• Treatment with anticoagulants or antiplatelet therapy other than aspirin

ALL OTHER GROUPS EXCEPT GREEN GROUP I

• History of autoimmune or traumatic pancreatitis, or acute necrotizing pancreatitis which results in suspected disconnected duct syndrome
• Primary pancreatic tumors, neuroendocrine tumors and other uncommon tumors