ACCESS-AP

Condition: Pancreatitis

Eligibility

Key Inclusion Criteria

  • 18-75 years old
  • Currently hospitalized with acute pancreatitis
  • TWEAK (screening test) alcohol consumption score of ≥3

Key Exclusion Criteria

  • Pancreatitis presumed to be related to gallstones, medication, trauma, autoimmune pancreatitis, post-ERCP pancreatitis, pancreatic ductal adenocarcinoma, suspected cystic neoplasm, neuroendocrine tumors and other uncommon tumors
  • Chronic pancreatitis with calcification(s)
  • Pancreatic cancer or pancreatic metastasis (cancer that has spread) from other malignancies

Full Study Name

ACCESS-AP: A Case-Crossover Study Design to Inform Tailored Interventions to Prevent Disease Progression in Acute Pancreatitis (IRB no. 00000364)

Summary

This study focuses on individuals who have been diagnosed with pancreatitis and consume alcohol. The purpose of the study is to examine health behaviors (including alcohol consumption, diet and smoking) that may contribute to the development of acute pancreatitis. Researchers aim to determine whether recent increase in alcohol consumption precipitates an attack of pancreatitis and whether the impact of alcohol is different for individuals who drink or smoke regularly. Participants will complete interviews about health behaviors, as well as provide blood and urine samples.

Another purpose of the study is to learn whether a biomarker test may help determine who is at higher risk for recurrence of pancreatitis. A biomarker is a biological molecule found in blood, urine, other body fluids or tissues that may be a sign of a condition or disease.

Principal Investigator

Christie Jeon, ScD

Contact
Felicity Pendergast
Phone: 310-423-0348
Email: felicity.pendergast@cshs.org