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28 results found


Nonalcoholic Fatty Liver Disease (NAFLD)

Resmetirom in Nonalcoholic Fatty Liver Disease

The purpose of this study is to determine the safety and effectiveness of an investigational drug called resmetirom in people with NASH/NAFLD and compensated cirrhosis. Specifically, the study will examine how well resmetirom works for ...


Liver cirrhosis, Portal hypertension

Zibotentan and Dapagliflozin, and Dapagliflozin Monotherapy in Cirrhosis

The purpose of this study is to learn more about the effects of 2 drugs, zibotentan and dapagliflozin, in people with liver disease (cirrhosis) with features of increased pressure in portal veins (portal hypertension). The ...


Other

Guselkumab and Golimumab in Ulcerative Colitis

The purpose of this study is to determine whether the experimental combination of guselkumab and golimumab is safe and effective for treating patients with moderately to severely active ulcerative colitis. Treatment with three different doses ...


Crohn's disease [regional enteritis]

Guselkumab and Golimumab in Crohn’s Disease

The purpose of this study is to determine whether the investigational combination of 2 drugs, guselkumab and golimumab, is safe and effective for treating patients with moderately to severely active Crohn’s disease. 3 different doses ...


Other

Auxora in Acute Pancreatitis and Accompanying Systemic Inflammatory Response Syndrome

The purpose of this study is to determine whether an experimental drug called Auxora is safe to use in people who have acute pancreatitis with accompanying systemic inflammatory response syndrome (SIRS). Acute pancreatitis with SIRS ...