Gastrointestinal Oncology Clinical Trials

Working together to constantly improve your diagnostic and treatment options, doctors and researchers at Cedars-Sinai are leaders in the field of gastroenterological disorders and gastrointestinal surgery. Hospitals around the world consult with our teams because of their expertise and history of groundbreaking discoveries. As a patient here, you'll have access to ongoing clinical trials and advanced research that provides treatment options to further advance your care—sometimes before it is widely available to others.

Questions? See the Clinical Trials FAQs.

Condition/Intervention:

  • Hepatocellular carcinoma

Key Inclusion Criteria:

  • At least 18 years old
  • Diagnosis of liver cirrhosis
  • Diagnosis of hepatocellular carcinoma

Summary:
This study focuses on individuals who have been diagnosed with an early-stage hepatocellular carcinoma (HCC) and who have been treated with therapies targeting the liver. The purpose of the study is to examine the effects that an investigational drug called pravastatin has on the time it takes for HCC to occur again in patients with early-stage HCC. Researchers believe that pravastatin, in combination with therapies targeting the liver, may delay or protect against HCC occurring again.

Condition/Intervention:

  • Cirrhosis

Key Inclusion Criteria:

  • At least 18 years old
  • Diagnosis of liver cirrhosis

Summary:
This study focuses on patients with liver cirrhosis (scarring of the liver which results in abnormal liver function). The purpose of the study is to compare the safety and effects of simvastatin in individuals with liver cirrhosis who are at an increased risk for liver cancer. Participants will receive either simvastatin or placebo (inactive substance). Simvastatin is approved by the U.S. Food and Drug Administration for various conditions, but its use in this study is investigational.