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Faculty Publications: Sept. 29-Oct. 6

A Comprehensive Digest of Research Publications From Cedars-Sinai Investigators

This week’s edition of Faculty Publications includes Cedars-Sinai studies that were published Sept. 29-Oct. 6. If you have a published paper from this period that does not appear on this list, please contact Sue Marone, who will add it to next week’s collection.

Biomedical Sciences 

Regulation of T-Independent B-Cell Responses by MicroRNA-146a. King, Jennifer K., Tiffany M. Tran, May H. Paing, Yuxin Yin, Amit K. Jaiswal, Ching-Hsuan Tso, Koushik Roy, David Casero, and Dinesh S. Rao. Frontiers in Immunology 13: 984302.

Fostering Scientific Innovation to Impact AKI: A Roadmap From ASN’s AKINow Basic Science Workgroup. Parikh, Samir M., Anupam Agarwal, Amandeep Bajwa, Sanjeev Kumar, Sherry G. Mansour, Mark D. Okusa, and Jorge Cerda. Kidney360 3 (8): 1445–48.


Effects of Risk Factors for Ovarian Cancer in Women With and Without Endometriosis. Phung, Minh Tung, Aruna Muthukumar, Britton Trabert, Penelope M. Webb, Susan J. Jordan, Kathryn L. Terry, Daniel W. Cramer, Linda J. Titus, Harvey A. Risch, Jennifer Anne Doherty, Holly R. Harris, Marc T. Goodman, Francesmary Modugno, Kirsten B. Moysich, Allan Jensen, Susanne K. Kjaer, Hoda Anton-Culver, Argyrios Ziogas, Andrew Berchuck, Lilah Khoja, Anna H. Wu, Malcolm C. Pike, Celeste Leigh Pearce, and Alice W. Lee. Fertility and Sterility, September, S0015-0282(22)00475-7.

Sentinel Lymph Node Biopsy in Patients With T1a Cutaneous Malignant Melanoma: A Multi-Center Cohort Study. Shannon, Adrienne B., Cimarron E. Sharon, Richard J. Straker, Michael J. Carr, Andrew J. Sinnamon, Kita Bogatch, Alexandra Thaler, Nicholas Kelly, John T. Vetto, Graham Fowler, Danielle DePalo, Vernon K. Sondak, John T. Miura, Mark B. Faries, Edmund K. Bartlett, Jonathan S. Zager, and Giorgos C. Karakousis. Journal of the American Academy of Dermatology, September, S0190-9622(22)02783-9.

Surgical Management of the Axilla in Breast Cancer: Evolving but Still Necessary. Schwartz, Theresa, Ashley D. Marumoto, and Armando E. Giuliano. Annals of Surgical Oncology, October.

Cardiac Surgery 

Robotic Degenerative Mitral Repair: Factors Associated With Intraoperative Revision and Impact of Mild Residual Regurgitation. Chen, Qiudong, Amy Roach, Alfredo Trento, Georgina Rowe, George Gill, Achille Peiris, Dominic Emerson, Danny Ramzy, Natalia Egorova, Michael E. Bowdish, and Joanna Chikwe. The Journal of Thoracic and Cardiovascular Surgery, August, S0022-5223(22)00823-6.

Heart Transplantation With Older Donors: Should There Be an Age Cutoff? Chen, Qiudong, Jon Kobashigawa, Dominic Emerson, Tahli Singer-Englar, Dominick Megna, Danny Ramzy, Pedro Catarino, Alfredo Trento, Joanna Chikwe, Michelle Kittleson, and Fardad Esmailian. Transplantation Proceedings, September, S0041-1345(22)00493-6.


Comparison of Residual Tricuspid Regurgitation Severity Assessed by Intraprocedural and Postprocedural Echocardiography in Patients Undergoing Transcatheter Tricuspid Valve Repair. Kuwajima, Ken, Shunsuke Kagawa, Takafumi Yamane, Hiroko Hasegawa, Moody Makar, Raj R. Makkar, and Takahiro Shiota. Journal of Cardiothoracic and Vascular Anesthesia, August, S1053-0770(22)00588-2.

Inhibitory Effect of Lanosterol on Cataractous Lens of Cynomolgus Monkeys Using a Subconjunctival Drug Release System. Zhang, Keke, Wenwen He, Yu Du, Yugui Zhou, Xiaokang Wu, Jie Zhu, Xiangjia Zhu, Kang Zhang, and Yi Lu. Precision Clinical Medicine 5 (3): pbac021.

Contributing Factors to Personalised Medicine in Atrial Fibrillation. Hendriks, Jeroen M., Adrian D. Elliott, Melissa E. Middeldorp, and Prashanthan Sanders. Heart (British Cardiac Society), September, heartjnl-2022-321553.

Excess Risk for Acute Myocardial Infarction Mortality During the COVID-19 Pandemic. Yeo, Yee Hui, Maggie Wang, Xinyuan He, Fan Lv, Yue Zhang, Jian Zu, Mei Li, Yang Jiao, Joseph E. Ebinger, Jignesh K. Patel, Susan Cheng, and Fanpu Ji. Journal of Medical Virology, September.

Ischemia With No Obstructive Arteries (INOCA): A Review of the Prevalence, Diagnosis and Management. Hansen, Breanna, Jessica N. Holtzman, Caroline Juszczynski, Najah Khan, Gurleen Kaur, Bhavya Varma, and Martha Gulati. Current Problems in Cardiology, September, 101420.

Periodontal Status, C-Reactive Protein, NT-ProBNP, and Incident Heart Failure: The ARIC Study. Molinsky, Rebecca L., Melana Yuzefpolskaya, Faye L. Norby, Bing Yu, Amil M. Shah, James S. Pankow, Chiadi E. Ndumele, Pamela L. Lutsey, Panos N. Papapanou, James D. Beck, Paolo C. Colombo, and Ryan T. Demmer. JACC. Heart Failure 10 (10): 731–41.

Initial Experience With a Continuous Mechanical Aspiration System for Thrombus Removal before Percutaneous Coronary Intervention. Mathews, S. Jay, Christopher L. Brown, Brian C. Kolski, Vasco M. Marques, Andrew Huynh, Suhail Y. Dohad, and Jon C. George. Catheterization and Cardiovascular Interventions, October.

Clinical Practice Variations in the Management of Ischemia With No Obstructive Coronary Artery Disease. Luu, Judy M., Janet Wei, Chrisandra L. Shufelt, Anum Asif, Benita Tjoe, Paul Theriot, and C. Noel Bairey Merz. Journal of the American Heart Association 11 (19): e022573.

Integration of Coronary Artery Calcium Scoring From CT Attenuation Scans by Machine Learning Improves Prediction of Adverse Cardiovascular Events in Patients Undergoing SPECT/CT Myocardial Perfusion Imaging. Feher, Attila, Konrad Pieszko, Robert Miller, Mark Lemley, Aakash Shanbhag, Cathleen Huang, Leonidas Miras, Yi-Hwa Liu, Albert J. Sinusas, Edward J. Miller, and Piotr J. Slomka. Journal of Nuclear Cardiology, October.

Mitigating Bias in Deep Learning for Diagnosis of Coronary Artery Disease From Myocardial Perfusion SPECT Images. Miller, Robert J. H., Ananya Singh, Yuka Otaki, Balaji K. Tamarappoo, Paul Kavanagh, Tejas Parekh, Lien-Hsin Hu, Heidi Gransar, Tali Sharir, Andrew J. Einstein, Mathews B. Fish, Terrence D. Ruddy, Philipp A. Kaufmann, Albert J. Sinusas, Edward J. Miller, Timothy M. Bateman, Sharmila Dorbala, Marcelo F. Di Carli, Joanna X. Liang, Damini Dey, Daniel S. Berman, and Piotr J. Slomka. European Journal of Nuclear Medicine and Molecular Imaging, October.

Proteomic Analysis of Diabetes Genetic Risk Scores Identifies Complement C2 and Neuropilin-2 as Predictors of Type 2 Diabetes: The Atherosclerosis Risk in Communities (ARIC) Study. Steffen, Brian T., Weihong Tang, Pamela L. Lutsey, Ryan T. Demmer, Elizabeth Selvin, Kunihiro Matsushita, Alanna C. Morrison, Weihua Guan, Mary R. Rooney, Faye L. Norby, Nathan Pankratz, David Couper, and James S. Pankow. Diabetologia, October.

Association Between Plaque Localization in Proximal Coronary Segments and MACE Outcomes in Patients With Mild CAC: Results From the EISNER Study. Tummala, Ramyashree, Donghee Han, John Friedman, Sean Hayes, Louise Thomson, Heidi Gransar, Piotr Slomka, Alan Rozanski, Damini Dey, and Daniel Berman. American Journal of Preventive Cardiology 12 (December): 100423.


Genetic and Environmental Factors Influencing Neonatal Resting-State Functional Connectivity. Blanchett, Reid, Yuanyuan Chen, Fernando Aguate, Kai Xia, Emil Cornea, S. Alexandra Burt, Gustavo de Los Campos, Wei Gao, John H. Gilmore, and Rebecca C. Knickmeyer. Cerebral Cortex (New York, N.Y.: 1991), October, bhac383.


Durable Biochemical Response and Safety With Oral Octreotide Capsules in Acromegaly. Samson, Susan L., Lisa B. Nachtigall, Maria Fleseriu, Mojca Jensterle, Patrick J. Manning, Atanaska Elenkova, Mark E. Molitch, William H. Ludlam, Gary Patou, Asi Haviv, Nienke R. Biermasz, Andrea Giustina, Christian J. Strasburger, Laurence Kennedy, and Shlomo Melmed. European Journal of Endocrinology, September, EJE-22-0220.

A Prospective Study of Lumbar Facet Arthroplasty in the Treatment of Degenerative Spondylolisthesis and Stenosis: Results From the Total Posterior Spine System (TOPS) IDE Study. Pinter, Zachariah W., Brett A. Freedman, Ahmad Nassr, Arjun S. Sebastian, Domagoj Coric, William C. Welch, Michael P. Steinmetz, Stephen E. Robbins, Jared Ament, Neel Anand, Paul Arnold, Eli Baron, Jason Huang, Robert Whitmore, Donald Whiting, David Tahernia, Faheem Sandhu, Ali Chahlavi, Joseph Cheng, John Chi, Stephen Pirris, Michael Groff, Alain Fabi, Scott Meyer, Vivek Kushwaha, Roland Kent, Steven DeLuca, Yossi Smorgick, Yoram Anekstein, and TOPS Study Group. Clinical Spine Surgery, August.

Cultural Humility and End-of-Life Communication With People With Advanced Liver Disease. Woodrell, Christopher D., Arpan A. Patel, Julius M. Wilder, Vinay Sundaram, Raymond T. Chung, and Nneka N. Ufere. Clinical Liver Disease 20 (3): 81–85.

Evidence of Premature Lymphocyte Aging in People With Low Anti-Spike Antibody Levels After BNT162b2 Vaccination. Huang, Yapei, Juliana E. Shin, Alexander Xu, Changfu Yao, Sandy Joung, Min Wu, Ruan Zhang, Bongha Shin, Joslyn Foley, Simeon B. Mahov, Matthew E. Modes, Joseph E. Ebinger, Matthew Driver, Jonathan G. Braun, Caroline A. Jefferies, Tanyalak Parimon, Chelsea Hayes, Kimia Sobhani, Akil Merchant, Sina A. Gharib, Stanley C. Jordan, Susan Cheng, Helen S. Goodridge, and Peter Chen. IScience, September, 105209.

Experiences as Editor of Obesity. Bergman, Richard N. Obesity (Silver Spring, Md.), September.

Association of Chronic Pancreatitis Pain Features With Physical, Mental and Social Health. Yadav, Dhiraj, Robert L. Askew, Tonya Palermo, Liang Li, Dana K. Andersen, Minxing Chen, William E. Fisher, Evan L. Fogel, Christopher E. Forsmark, Phil A. Hart, Mohamed O. Othman, Stephen J. Pandol, Walter G. Park, Mark D. Topazian, Stephen K. Van Den Eeden, Santhi Swaroop Vege, Yunlong Yang, Jose Serrano, Darwin L. Conwell, and Consortium for the Study of Chronic Pancreatitis, Diabetes, and Pancreatic Cancer (CPDPC). Clinical Gastroenterology and Hepatology, September, S1542-3565(22)00924-7.

Concordance and Discordance Between Patient-Reported Remission, Patient-Reported Outcomes, and Physician Global Assessment. Kamp, Kendra J., Stephen E. Hawes, Chung Sang Tse, Siddharth Singh, Nhu Dang, Ridhima Oberai, S. Alandra Weaver, Gil Y. Melmed, Corey A. Siegel, Welmoed K. van Deen, and IBD Qorus. Inflammatory Bowel Diseases, September, izac206.

Placebo Adverse Events in Non-Alcoholic Steatohepatitis Clinical Trials. A Pooled Analysis of 2,944 Participants. Lin Tay, Phoebe Wen, Cheng Han Ng, Snow Yunni Lin, Yip Han Chin, Jieling Xiao, Wen Hui Lim, Sze Yinn Lim, Clarissa Elysia Fu, Kai En Chan, Jingxuan Quek, Darren Jun Hao Tan, Nicholas Chew, Nicholas Syn, Taisei Keitoku, Nobuharu Tamaki, Mohammad Shadab Siddiqui, Mazen Noureddin, Mark Muthiah, Daniel Q. Huang, and Rohit Loomba. The American Journal of Gastroenterology, September.

Gender, Race, and Ethnicity Representation Among Gastroenterologists: A Review of Recent Trends. Rahal, Harman, Mohit Girotra, Folasade P. May, and James H. Tabibian. The American Journal of Gastroenterology 117 (10): 1566–72.

Response to Sachdeva et Al. Takakura, Will, and Ali Rezaie. The American Journal of Gastroenterology 117 (10): 1718.

Targeting A-Kinase Anchoring Protein 12 Phosphorylation in Hepatic Stellate Cells Regulates Liver Injury and Fibrosis in Mouse Models. Ramani, Komal, Nirmala Mavila, Aushinie Abeynayake, Maria Lauda Tomasi, Jiaohong Wang, Michitaka Matsuda, and Eki Seki. ELife 11 (October): e78430.

Deletion of Adipocyte Prohibitin 1 Exacerbates High-Fat Diet-Induced Steatosis but Not Liver Inflammation and Fibrosis. Wang, Xiaolin, Seung-Jin Kim, Yukun Guan, Richard Parker, Robim M. Rodrigues, Dechun Feng, Shelly C. Lu, and Bin Gao. Hepatology Communications, October.

The Placebo Response Rate and Nocebo Events in Obesity Pharmacological Trials. A Systematic Review and Meta-Analysis. Chin, Yip Han, Cheng Han Ng, Nicholas Ws Chew, Gwyneth Kong, Wen Hui Lim, Darren Jun Hao Tan, Kai En Chan, Ansel Tang, Daniel Q. Huang, Mark Y. Chan, Gemma Figtree, Jiong-Wei Wang, Asim Shabbir, Chin Meng Khoo, Vincent Wai-Sun Wong, Dan Yock Young, Mohammad Shadab Siddiqui, Mazen Noureddin, Arun Sanyal, David E. Cummings, Nicholas Syn, and Mark Dhinesh Muthiah. EClinicalMedicine 54 (December): 101685.


Familial Bainbridge-Ropers Syndrome: Report of Familial ASXL3 Inheritance and a Milder Phenotype. Schirwani, Schaida, Emily Woods, David A. Koolen, Charlotte W. Ockeloen, Sally Ann Lynch, Karl Kavanagh, John M. Graham, Katheryn Grand, Tyler Mark Pierson, Jeffrey M. Chung, and Meena Balasubramanian. American Journal of Medical Genetics. Part A, September.

Allostatic Load Predicts Racial Disparities in Intracerebral Hemorrhage Cognitive Outcomes. Harris, Jennifer, Amelia Boehme, Luisa Chan, Harmon Moats, Rachelle Dugue, Chigozirim Izeogu, Marykay A. Pavol, Imama A. Naqvi, Olajide Williams, and Randolph S. Marshall. Scientific Reports 12 (1): 16556.


Surgery as a First-Line Option for Prolactinomas. Mamelak, Adam. Expert Review of Endocrinology & Metabolism, October, 1–14.


Anxiety in Pregnancy and Length of Gestation: Findings From the Healthy Babies Before Birth Study. Dunkel Schetter, Christine, Danny Rahal, Carolyn Ponting, Melissa Julian, Isabel Ramos, Calvin J. Hobel, and Mary Coussons-Read. Health Psychology, September.


Socioeconomic Factors Affecting Outcomes in Total Knee and Hip Arthroplasty: A Systematic Review on Healthcare Disparities. Alvarez, Paul M., John F. McKeon, Andrew I. Spitzer, Chad A. Krueger, Matthew Pigott, Mengnai Li, and Sravya P. Vajapey. Arthroplasty (London, England) 4 (1): 36.


Leishmaniasis and Chagas Disease: Is There Hope in Nanotechnology to Fight Neglected Tropical Diseases? Scariot, Debora B., Austeja Staneviciute, Jennifer Zhu, Xiaomo Li, Evan A. Scott, and David M. Engman. Frontiers in Cellular and Infection Microbiology 12: 1000972.

Investigating Anti-D in an Individual With the Weak D Type 2 Genotype. Phou, S., N. Nguyen, J. Revilla, K. Rodberg, D. R. Gibb, S. H. Pepkowitz, and E. B. Klapper. Immunohematology 38 (3): 77–81.

Are Sunscreen Particles Involved in Frontal Fibrosing Alopecia?-A TEM-EDXS Analysis on Formalin-Fixed Paraffin-Embedded Alopecia Biopsies (Pilot Study). Abuav, Rachel, and Wonwoo Shon. The American Journal of Dermatopathology, September.

Comparative Upper Respiratory Tract Transcriptomic Profiling Reveals a Potential Role of Early Activation of Interferon Pathway in Severe COVID-19. Bhat, Shabir A., Tomohiro Shibata, Matthew Leong, Jasmine Plummer, Eric Vail, and Zakir Khan. Viruses 14 (10): 2182.

Changes in Coagulation Testing During a National Shortage of Blue-Top Tubes. Schuett, Hannah G., Oksana Volod, Anders H. Berg, Kyu Rhee, Sam S. Torbati, Richard V. Riggs, and David P. Frishberg. American Journal of Clinical Pathology, October, aqac121.

Radiation Oncology 

GEC-ESTRO (ACROP) - ABS - CBG Consensus Brachytherapy Target Definition Guidelines for Recurrent Endometrial and Cervical Tumors in the Vagina. Kamrava, Mitchell, Eric Leung, Francois Bachand, Sushil Beriwal, Cyrus Chargari, David D’Souza, Beth Erickson, Lars Fokdal, Kathy Han, Matthew Harkenrider, Lilie Lin, Umesh Mahantshetty, Nicole Nesvacil, Ananth Ravi, Max Schmid, Eric Vigneault, Henrike Westerveld, Catheryn Yashar, and Remi Nout. International Journal of Radiation Oncology, Biology, Physics, September, S0360-3016(22)03396-X.


An Alternative Option for Gender-Affirming Revision Vaginoplasty: The Tubularized Urachus-Peritoneal Hinge Flap. Smith, Shannon M., Nance Yuan, Jenna Stelmar, Grace Lee Pa-C, Amit Gupta, Hyung L. Kim, and Maurice M. Garcia. Sexual Medicine 10 (6): 100572.

Laryngotracheal Recurrent Papillomatosis: A Case Study and Survey of Surgical and Systemic Management. Borrelli, Michela, Tasha Nasrollahi, Jonathan Raskin, Sana Khan, and Ronda E. Alexander. Ear, Nose, & Throat Journal, September, 1455613221128714.

Severe Airway Edema Following Calcium Hydroxylapatite (CaHA) Injection Augmentation. Borrelli, Michela, Tasha Nasrollahi, Jonathan Raskin, Sana Khan, and Omid B. Mehdizadeh. Ear, Nose, & Throat Journal, September, 1455613221127584.