Faculty Publications: Sept. 15-22

This week’s edition of Faculty Publications includes Cedars-Sinai studies that were published Sept. 15-22. If you have a published paper from this period that does not appear on this list, please contact Sue Marone, who will add it to next week’s collection.

Anesthesiology

Measuring and Reporting Quality for Adult Extracorporeal Membrane Oxygenation Centers: Is It Possible and Is It Time? Mazzeffi, Michael A., Megan Krajewski, Kenneth Shelton, Adam Dalia, Farzad Najam, Jacob Gutsche, and Michael Nurok. Anesthesia and Analgesia 135 (4): 719–24.

Cancer

Photobiomodulation Therapy in Management of Cancer Therapy-Induced Side Effects: WALT Position Paper. Robijns, Jolien, Raj G. Nair, Joy Lodewijckx, Praveen Arany, Andrei Barasch, Jan M. Bjordal, Paolo Bossi, Anne Chilles, Patricia M. Corby, Joel B. Epstein, Sharon Elad, Reza Fekrazad, Eduardo Rodrigues Fregnani, Marie-Thérèse Genot, Ana M. C. Ibarra, Michael R. Hamblin, Vladimir Heiskanen, Ken Hu, Jean Klastersky, Rajesh Lalla, Sofia Latifian, Arun Maiya, Jeroen Mebis, Cesar A. Migliorati, Dan M. J. Milstein, Barbara Murphy, Judith E. Raber-Durlacher, Hendrik J. Roseboom, Stephen Sonis, Nathaniel Treister, Yehuda Zadik, and René-Jean Bensadoun. Frontiers in Oncology 12: 927685.

Splenectomy at the Time of Primary or Interval Cytoreductive Surgery for Epithelial Ovarian Carcinoma: A Review of Outcomes. Rush, Shannon K., Brittany F. Lees, Dandi S. Huang, Megan F. Peterson, and Ahmed Al-Niaimi. Gynecologic Oncology, September, S0090-8258(22)00577-7.

Defining New Reference Intervals for Serum Free Light Chains in Individuals With Chronic Kidney Disease: Results of the IStopMM Study. Long, Thorir Einarsson, Olafur Skuli Indridason, Runolfur Palsson, Sæmundur Rognvaldsson, Thorvardur Jon Love, Sigrun Thorsteinsdottir, Ingigerdur Solveig Sverrisdottir, Brynjar Vidarsson, Pall Torfi Onundarson, Bjarni Agnar Agnarsson, Margret Sigurdardottir, Ingunn Thorsteinsdottir, Isleifur Olafsson, Asdis Rosa Thordardottir, Elias Eythorsson, Asbjorn Jonsson, Gauti Gislason, Andri Olafsson, Hlif Steingrimsdottir, Malin Hultcrantz, Brian G. M. Durie, Stephen Harding, Ola Landgren, and Sigurdur Yngvi Kristinsson. Blood Cancer Journal 12 (9): 133.

Expanded Parameters in Active Surveillance for Low-Risk Papillary Thyroid Carcinoma: A Nonrandomized Controlled Trial. Ho, Allen S., Sungjin Kim, Cynthia Zalt, Michelle L. Melany, Irene E. Chen, Joan Vasquez, Jon Mallen-St Clair, Michelle M. Chen, Missael Vasquez, Xuemo Fan, Welmoed K. van Deen, Robert W. Haile, Timothy J. Daskivich, Zachary S. Zumsteg, Glenn D. Braunstein, and Wendy L. Sacks. JAMA Oncology, September.

Tet2 Helps Blood Cells Balance in Air. Chute, John P. Blood 140 (11): 1186–87.

A General Class of Promotion Time Cure Rate Models With a New Biological Interpretation. Gómez, Yolanda M., Diego I. Gallardo, Marcelo Bourguignon, Eduardo Bertolli, and Vinicius F. Calsavara. Lifetime Data Analysis, September.

Blood Plasma Derived Extracellular Vesicles (BEVs): Particle Purification Liquid Chromatography (PPLC) and Proteomic Analysis Reveals BEVs as a Potential Minimally Invasive Tool for Predicting Response to Breast Cancer Treatment. Alvarez, Folnetti A., Hussein Kaddour, Yuan Lyu, Christina Preece, Jules Cohen, Lea Baer, Alison T. Stopeck, Patricia Thompson, and Chioma M. Okeoma. Breast Cancer Research and Treatment, September.

Single-Cell Profile of Tumor and Immune Cells in Primary Breast Cancer, Sentinel Lymph Node, and Metastatic Lymph Node. Liao, Ning, Cheukfai Li, Li Cao, Yanhua Chen, Chongyang Ren, Xiaoqing Chen, Hsiaopei Mok, Lingzhu Wen, Kai Li, Yulei Wang, Yuchen Zhang, Yingzi Li, Jiaoyi Lv, Fangrong Cao, Yuting Luo, Hongrui Li, Wendy Wu, Charles M. Balch, and Armando E. Giuliano. Breast Cancer (Tokyo, Japan), September.

Cardiac Surgery 

DKS Reconstruction and LPA Size. Emerson, Dominic, M. Mujeeb Zubair, and Richard W. Kim. The Annals of Thoracic Surgery, September, S0003-4975(22)01216-4.

Cardiology

Cerebral Embolic Protection During Transcatheter Aortic-Valve Replacement. Kapadia, Samir R., Raj Makkar, Martin Leon, Mohamed Abdel-Wahab, Thomas Waggoner, Steffen Massberg, Wolfgang Rottbauer, Samuel Horr, Lars Sondergaard, Juhana Karha, Robert Gooley, Lowell Satler, Robert C. Stoler, Steven R. Messé, Suzanne J. Baron, Julia Seeger, Susheel Kodali, Amar Krishnaswamy, Vinod H. Thourani, Katherine Harrington, Stuart Pocock, Rodrigo Modolo, Dominic J. Allocco, Ian T. Meredith, Axel Linke, and PROTECTED TAVR Investigators. The New England Journal of Medicine, September.

Deep Learning for Explainable Estimation of Mortality Risk From Myocardial Positron Emission Tomography Images. Singh, Ananya, Jacek Kwiecinski, Robert J. H. Miller, Yuka Otaki, Paul B. Kavanagh, Serge D. Van Kriekinge, Tejas Parekh, Heidi Gransar, Konrad Pieszko, Aditya Killekar, Ramyashree Tummala, Joanna X. Liang, Marcelo F. Di Carli, Daniel S. Berman, Damini Dey, and Piotr J. Slomka. Circulation. Cardiovascular Imaging 15 (9): e014526.

Sports Cardiology: The Transition of Fellow-in-Training to Early Career Physician. Husaini, Mustafa, Kristopher P. Kline, Merije Chukumerije, Michael S. Emery, Matthew W. Martinez, and Eugene H. Chung.JACC. Case Reports 4 (17): 1143–46.

Randomized Comparison of Transcatheter Edge-to-Edge Repair for Degenerative Mitral Regurgitation in Prohibitive Surgical Risk Patients. Lim, D. Scott, Robert L. Smith, Linda D. Gillam, Firas Zahr, Scott Chadderdon, Raj Makkar, Ralph Stephan von Bardeleben, Robert M. Kipperman, Andrew N. Rassi, Molly Szerlip, Scott Goldman, Ignacio Inglessis-Azuaje, Pradeep Yadav, Philipp Lurz, Charles J. Davidson, Mubashir Mumtaz, Hemal Gada, Saibal Kar, Susheel K. Kodali, Roger Laham, William Hiesinger, Neil P. Fam, Mirjam Keßler, William W. O’Neill, Brian Whisenant, Chad Kliger, Samir Kapadia, Volker Rudolph, Joseph Choo, James Hermiller, Michael A. Morse, Niklas Schofer, Sameer Gafoor, Azeem Latib, Konstantinos Koulogiannis, Leo Marcoff, Jörg Hausleiter, and CLASP IID Pivotal Trial Investigators. JACC. Cardiovascular Interventions, September, S1936-8798(22)01704-6.

Serial Changes in Troponin I in COVID-19 Vaccine-Associated Myocarditis. Aldana-Bitar, Jairo, Noah R. Ramirez, Allan S. Jaffe, Venkat S. Manubolu, Dhiran Verghese, Luay Hussein, Lauren R. Anderson, Matthew J. Budoff, and Ronald P. Karlsberg. Cardiology Research 13 (4): 250–54.

Early Identification and Treatment of Women’s Cardiovascular Risk Factors Prevents Cardiovascular Disease, Saves Lives, and Protects Future Generations: Policy Recommendations and Take Action Plan Utilizing Policy Levers. Ivey, Susan L., Hattie Rees Hanley, Catrina Taylor, Eveline Stock, Nirali Vora, Jenny Woo, Sara Johnson, C. Noel Bairey Merz, and Right Care Women’s Cardiovascular Writing Group. Clinical Cardiology, September.

Computational Biomedicine 

Knowledge-Guided Deep Learning Models of Drug Toxicity Improve Interpretation. Hao, Yun, Joseph D. Romano, and Jason H. Moore. Patterns (New York, N.Y.) 3 (9): 100565.

Multi-Omic Integration by Machine Learning (MIMaL). Dickinson, Quinn, Andreas Aufschnaiter, Martin Ott, and Jesse G. Meyer. Bioinformatics (Oxford, England), September, btac631.

Automatically Identifying Twitter Users for Interventions to Support Dementia Family Caregivers: Annotated Data Set and Benchmark Classification Models. Klein, Ari Z., Arjun Magge, Karen O’Connor, and Graciela Gonzalez-Hernandez. JMIR Aging 5 (3): e39547.

Imaging

CAD-RADS^TM 2.0 - 2022 Coronary Artery Disease-Reporting and Data System: An Expert Consensus Document of the Society of Cardiovascular Computed Tomography (SCCT), the American College of Cardiology (ACC), the American College of Radiology (ACR), and the North America Society of Cardiovascular Imaging (NASCI). Cury, Ricardo C., Jonathon Leipsic, Suhny Abbara, Stephan Achenbach, Daniel Berman, Marcio Bittencourt, Matthew Budoff, Kavitha Chinnaiyan, Andrew D. Choi, Brian Ghoshhajra, Jill Jacobs, Lynne Koweek, John Lesser, Christopher Maroules, Geoffrey D. Rubin, Frank J. Rybicki, Leslee J. Shaw, Michelle C. Williams, Eric Williamson, Charles S. White, Todd C. Villines, and Ron Blankstein. JACC. Cardiovascular Imaging, September, S1936-878X(22)00401-6.

Ischemia With Nonobstructive Coronary Arteries: Insights From the ISCHEMIA Trial. Reynolds, Harmony R., Ariel Diaz, Derek D. Cyr, Leslee J. Shaw, G. B. John Mancini, Jonathon Leipsic, Matthew J. Budoff, James K. Min, Cameron J. Hague, Daniel S. Berman, Bernard R. Chaitman, Michael H. Picard, Sean W. Hayes, Marielle Scherrer-Crosbie, Raymond Y. Kwong, Renato D. Lopes, Roxy Senior, Sudhanshu K. Dwivedi, Todd D. Miller, Benjamin J. W. Chow, Ramesh de Silva, Gregg W. Stone, William E. Boden, Sripal Bangalore, Sean M. O’Brien, Judith S. Hochman, David J. Maron, and ISCHEMIA Research Group. JACC. Cardiovascular Imaging, September, S1936-878X(22)00406-5.

MR Multitasking-Based Dynamic Imaging for Cerebrovascular Evaluation (MT-DICE): Simultaneous Quantification of Permeability and Leakage-Insensitive Perfusion by Dynamic  T 1 / T 2 *   Mapping. Hu, Zhehao, Anthony G. Christodoulou, Nan Wang, Yibin Xie, Mark S. Shiroishi, Wensha Yang, Gabriel Zada, Frances E. Chow, Ashley S. Margol, Benita Tamrazi, Eric L. Chang, Debiao Li, and Zhaoyang Fan. Magnetic Resonance in Medicine, September.

Medicine

Methanogens and Hydrogen Sulfide Producing Bacteria Guide Distinct Gut Microbe Profiles and Irritable Bowel Syndrome Subtypes. Villanueva-Millan, Maria J., Gabriela Leite, Jiajing Wang, Walter Morales, Gonzalo Parodi, Maya L. Pimentel, Gillian M. Barlow, Ruchi Mathur, Ali Rezaie, Maritza Sanchez, Sarah Ayyad, Daniel Cohrs, Christine Chang, Mohamad Rashid, Ava Hosseini, Alyson Fiorentino, Stacy Weitsman, Brennan Chuang, Bianca Chang, Nipaporn Pichetshote, and Mark Pimentel. The American Journal of Gastroenterology, September.

Using a Knowledge Translation Program to Facilitate Guideline- and Evidence-Based Patient Management: The PAH-QuERI Extension Program. McLaughlin, Vallerie V., Richard N. Channick, Karimah S. Bell Lynum, Ronald J. Oudiz, Mona Selej, Victor F. Tapson, and Lewis J. Rubin. Pulmonary Circulation 12 (3): e12134.

Acid-Suppressive Therapy Among Infants and Risk of Anemia at 12 Months of Age. Abu-Sulb, Ahmad, Rawan Al-Najjar, Rama Maghnam, and Ashraf Ashhab. SAGE Open Medicine 10: 20503121221123116.

Inhaled Treprostinil Dose in Pulmonary Hypertension Associated With Interstitial Lung Disease and Its Effects on Clinical Outcomes. Nathan, Steven D., Chunqin Deng, Christopher S. King, Hilary M. DuBrock, Jean Elwing, Sudarshan Rajagopal, Franz Rischard, Sandeep Sahay, Meredith Broderick, Eric Shen, Peter Smith, Victor F. Tapson, and Aaron B. Waxman. Chest, September, S0012-3692(22)03725-4.

Effects of Supplementation With Low-Dose Group B Vitamins on Clinical and Biochemical Parameters in Critically Ill Patients With COVID-19: A Randomized Clinical Trial. Majidi, Nazanin, Effat Bahadori, Soheila Shekari, Maryam Gholamalizadeh, Shirin Tajaddod, Marjan Ajami, Somayeh Gholami, Mahdi Shadnoush, Mina Ahmadzadeh, Anoush Dehnadi Moghadam, Naeemeh Hassanpour, Hanieh Shafahi, Fatemeh Shafie, Alireza Moslem, Saeid Doaei, and Mark O. Goodarzi. Expert Review of Anti-Infective Therapy, September.

The Quality of Occupational Healthcare for Carpal Tunnel Syndrome, Healthcare Expenditures, and Disability Outcomes: A Prospective Observational Study. Nuckols, Teryl K., Michael Dworsky, Craig Conlon, Michael Robbins, Douglas Benner, Seth Seabury, and Steven M. Asch. Muscle & Nerve, September.

Forecasted 2040 Global Prevalence of NAFLD Using Hierarchical Bayesian Approach. Le, Michael H., Yee Hui Yeo, Biyao Zou, Scott Barnet, Linda Henry, Ramsey Cheung, and Mindie H. Nguyen. Clinical and Molecular Hepatology, September.

A New Model for Identification of HBV-Related Pre-ACLF. Jalan, Rajiv, and Vinay Sundaram. JHEP Reports: Innovation in Hepatology 4 (10): 100554.

Randomized Trial of Tocilizumab in the Treatment of Refractory Adult Polymyositis and Dermatomyositis. Oddis, Chester V., Howard E. Rockette, Lei Zhu, Diane C. Koontz, David Lacomis, Swamy Venturupalli, Siamak Moghadam-Kia, Dana P. Ascherman, Leslie Crofford, Mazen M. Dimachkie, Floranne Ernste, David Gazeley, Galina Marder, and Rohit Aggarwal. ACR Open Rheumatology, September.

Neurology

Systemic Interleukin-6 Inhibition Ameliorates Acute Neuropsychiatric Phenotypes in a Murine Model of Acute Lung Injury. Anwar, Faizan, Nicklaus A. Sparrow, Mohammad Harun Rashid, Gena Guidry, Michael M. Gezalian, Eric J. Ley, Maya Koronyo-Hamaoui, Itai Danovitch, E. Wesley Ely, S. Ananth Karumanchi, and Shouri Lahiri. Critical Care (London, England) 26 (1): 274.

Neurosurgery

ZEB1 Loss Increases Glioma Stem Cell Tumorigenicity and Resistance to Chemoradiation. Hanna, George K., Mecca Madany, Angelique Sao-Mai Sy Tay, Lincoln A. Edwards, Sungjin Kim, Justin S. Michael, Miriam Nuno, Tom Thomas, Aiguo Li, Dror Berel, Keith L. Black, Xuemo Fan, Wei Zhang, Jeremy D. Rudnick, Rongfu Wang, and John S. Yu. Journal of Neurosurgery, September, 1–12.

OBGYN

Sex at the Interface: The Origin and Impact of Sex Differences in the Developing Human Placenta. Braun, Amy E., Olivia R. Mitchel, Tania L. Gonzalez, Tianyanxin Sun, Amy E. Flowers, Margareta D. Pisarska, and Virginia D. Winn. Biology of Sex Differences 13 (1): 50.

Pathology

Surveillance Diagnostic Algorithm Using Real-Time PCR Assay and Strain Typing Method Development to Assist With the Control of C. Auris amid COVID-19 Pandemic. Contreras, Deisy A., and Margie A. Morgan. Frontiers in Cellular and Infection Microbiology 12: 887754.

Viscoelastic Testing in the Management of Adult Patients on Mechanical Circulatory Support Devices With Focus on Extracorporeal Membrane Oxygenation. Volod, Oksana, and Julie Wegner. Seminars in Thrombosis and Hemostasis, September.

Failure of Human Rhombic Lip Differentiation Underlies Medulloblastoma Formation. Hendrikse, Liam D., Parthiv Haldipur, Olivier Saulnier, Jake Millman, Alexandria H. Sjoboen, Anders W. Erickson, Winnie Ong, Victor Gordon, Ludivine Coudière-Morrison, Audrey L. Mercier, Mohammad Shokouhian, Raúl A. Suárez, Jeffrey A. Golden, Michael D. Taylor, et al. Nature, September.

Organoid-on-a-Chip Model of Human ARPKD Reveals Mechanosensing Pathomechanisms for Drug Discovery. Hiratsuka, Ken, Tomoya Miyoshi, Katharina T. Kroll, Navin R. Gupta, M. Todd Valerius, Thomas Ferrante, Michifumi Yamashita, Jennifer A. Lewis, and Ryuji Morizane. Science Advances 8 (38): eabq0866.

Pediatrics

PIK3CA-Related Overgrowth Spectrum. Mirzaa, Ghayda, John M. Graham, and Kim Keppler-Noreuil. In GeneReviews®, edited by Margaret P. Adam, David B. Everman, Ghayda M. Mirzaa, Roberta A. Pagon, Stephanie E. Wallace, Lora JH Bean, Karen W. Gripp, and Anne Amemiya. Seattle (WA): University of Washington, Seattle.

Is the Choroid Plexus Needed? Stricker, Sarah, Raphael Guzman, Thomas Blauwblomme, and Moise Danielpour. Pediatric Neurosurgery, August.

Technical Outcomes in Pediatric Endoscopic Retrograde Cholangiopancreatography: Data From an International Collaborative. Troendle, David M., Wenly Ruan, Douglas S. Fishman, Bradley A. Barth, Quin Y. Liu, Matthew Giefer, Kyung Mo Kim, Mercedes Martinez, Luigi Dall’oglio, Filippo Torroni, Paola De Angelis, Simona Faraci, Sam Bitton, Michael Wilsey, Racha Khalaf, Steven Werlin, Kulwinder Dua, Roberto Gugig, Clifton Huang, Petar Mamula, J. Antonio Quiros, Yuhua Zheng, Amit Grover, and Victor L. Fox. Journal of Pediatric Gastroenterology and Nutrition, September.

An HNRNPK-Specific DNA Methylation Signature Makes Sense of Missense Variants and Expands the Phenotypic Spectrum of Au-Kline Syndrome. Choufani, Sanaa, Vanda McNiven, Cheryl Cytrynbaum, Maryam Jangjoo, Margaret P. Adam, Hans T. Bjornsson, Jacqueline Harris, David A. Dyment, Gail E. Graham, Marjan M. Nezarati, Ritu B. Aul, Claudia Castiglioni, Rosanna Weksberg, et al. American Journal of Human Genetics, September, S0002-9297(22)00403-7.

Radiation Oncology 

The Addition of Pelvic Lymph Node Treatment to Prostate Bed Salvage Radiotherapy - Authors’ Reply. Pollack, Alan, Theodore G. Karrison, Felix Feng, Oliver Sartor, and Howard M. Sandler. Lancet (London, England) 400 (10356): 885–86.

Surgery

Medical Malpractice Trends in Dacryocystorhinostomy and Orbital Decompression. Tang, Dennis M, Rachna Goli, Thomas S Higgins, Jonathan Y Ting, Elisa A Illing, and Arthur W Wu. American Journal of Rhinology & Allergy, September, 19458924221118140.

Increased Prevalence of Eosinophilic Esophagitis in Patients With Chronic Rhinosinusitis. Simmons, Jordan K., David A. Leiman, Sarita U. Patil, Edward McCoul, Philip G. Chen, Dennis M. Tang, Edward C. Kuan, Elena E. Chang, and Arthur W. Wu. American Journal of Rhinology & Allergy, September, 19458924221116160.

Minimally Invasive Surgery in the United States, 2022: Understanding Its Value Using New Datasets. Mattingly, Aviva S., Michelle M. Chen, Vasu Divi, F. Christopher Holsinger, and Anirudh Saraswathula. The Journal of Surgical Research 281 (September): 33–36.

SupportiNg OperAtive Photo Documentation in Ileocolonic CROHN’s Disease Surgery - the SNAPCROHN Study. Celentano, V., M. Adamina, A. Spinelli, P. Fleshner, G. Pellino, M. Mineccia, F. Selvaggi, M. Svrcek, P. Tozer, E. Espin-Basany, L. Hancock, O. Faiz, C. J. Coffey, and G. Sampietro. Colorectal Disease, September.

Clinical Ethics Consultations and the Necessity of NOT Meeting Expectations: I Never Promised You a Rose Garden. Finder, Stuart G., and Virginia L. Bartlett. HEC Forum: An Interdisciplinary Journal on Hospitals’ Ethical and Legal Issues, September.

Metastatic Skull Base Chordoma: A Systematic Review. Young, Kurtis, Torbjoern Nielsen, Hannah Bulosan, Tyler J. Thorne, Christian T. Ogasawara, Andrew C. Birkeland, Dennis M. Tang, Arthur W. Wu, and Toby O. Steele. Laryngoscope Investigative Otolaryngology n/a (n/a). Accessed September 21.