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2022
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Faculty Publications: Oct. 27-Nov. 3

A Comprehensive Digest of Research Publications From Cedars-Sinai Investigators

This week’s edition of Faculty Publications includes Cedars-Sinai studies that were published Oct. 27-Nov. 3. If you have a published paper from this period that does not appear on this list, please contact Sue Marone, who will add it to next week’s collection.

Biomedical Sciences 

Intramyocardial Hemorrhage Drives Fatty Degeneration of Infarcted Myocardium. Cokic, Ivan, Shing Fai Chan, Xingmin Guan, Anand R. Nair, Hsin-Jung Yang, Ting Liu, Yinyin Chen, Diego Hernando, Jane Sykes, Richard Tang, John Butler, Alice Dohnalkova, Libor Kovarik, Robert Finney, Avinash Kali, Behzad Sharif, Louis S. Bouchard, Rajesh Gupta, Mayil Singaram Krishnam, Keyur Vora, Balaji Tamarappoo, Andrew G. Howarth, Andreas Kumar, Joseph Francis, Scott B. Reeder, John C. Wood, Frank S. Prato, and Rohan Dharmakumar. Nature Communications 13 (1): 6394.

Multisite Evaluation of Prediction Models for Emergency Department Crowding Before and During the COVID-19 Pandemic. Smith, Ari J., Brian W. Patterson, Michael S. Pulia, John Mayer, Rebecca J. Schwei, Radha Nagarajan, Frank Liao, Manish N. Shah, and Justin J. Boutilier. Journal of the American Medical Informatics Association: JAMIA, October, ocac214.

Pathogenesis of Cardiomyopathy Caused by Variants in ALPK3, an Essential Pseudokinase in the Cardiomyocyte Nucleus and Sarcomere. Agarwal, Radhika, Hiroko Wakimoto, Joao A. Paulo, Qi Zhang, Daniel Reichart, Christopher Toepfer, Arun Sharma, Angela C. Tai, Mingyue Lun, Joshua Gorham, Steven R. DePalma, Steven P. Gygi, J. G. Seidman, and Christine E. Seidman. Circulation, November.

Cancer

The 17-Gene Genomic Prostate Score® Test Is Prognostic for Outcomes After Primary External Beam Radiation Therapy in Men With Clinically Localized Prostate Cancer. Janes, Jessica L., Matthew J. Boyer, John Bennett, Vanessa M. Thomas, Amanda M. De Hoedt, David K. Edwards V, Purva K. Singla, John Abran, Tamer Aboushwareb, Joseph K. Salama, and Stephen J. Freedland. International Journal of Radiation Oncology, Biology, Physics, July, S0360-3016(22)00718-0.

First-in-Human Study of an OX40 (Ivuxolimab) and 4-1BB (Utomilumab) Agonistic Antibody Combination in Patients With Advanced Solid Tumors. Hamid, Omid, Alberto A. Chiappori, John A. Thompson, Toshihiko Doi, Siwen Hu-Lieskovan, Ferry A. L. M. Eskens, Willeke Ros, Adi Diab, Jean-Philippe Spano, Naiyer A. Rizvi, Jeffrey S. Wasser, Eric Angevin, Patrick A. Ott, Alison Forgie, Wenjing Yang, Cen Guo, Jeffrey Chou, and Anthony B. El-Khoueiry. Journal for Immunotherapy of Cancer 10 (10): e005471.

Harnessing Antibody Polyspecificity for Cancer Immunotherapy. Pashov, Anastas, Ramachandran Murali, Issam Makhoul, Behjatolah Karbassi, and Thomas Kieber-Emmons. Monoclonal Antibodies in Immunodiagnosis and Immunotherapy 41 (5): 290–300.

EGFR Pathway Targeting Drugs in Head and Neck Cancer in the Era of Immunotherapy. Kang, James J., Albert Ko, Sang Hoon Kil, Jon Mallen-St Clair, Daniel Sanghoon Shin, Marilene B. Wang, and Eri S. Srivatsan. Biochimica Et Biophysica Acta. Reviews on Cancer, October, 188827.

Correspondence on ‘The Increasing Incidence of Stage IV Cervical Cancer in the USA: What Factors Are Related?’ By Francoeur et Al. Datta, Geetanjali D., Marie-Helene Mayrand, and Beth A. Glenn. International Journal of Gynecological Cancer, October, ijgc–2022–004066.

Association Between Results From the 17-Gene Genomic Prostate Score Assay and Long-Term Outcomes After External Beam Radiation Therapy in Intermediate- or High-Risk Prostate Cancer Patients, Independent of Race. Boyer, M.J., J. Janes, J. Bennett, V. Thomas, A. De Hoedt, J. Abran, T. Aboushwareb, J.K. Salama, and S.J. Freedland. International Journal of Radiation Oncology, Biology, Physics 114 (3): e213–e213.

Increased FOXJ1 Protein Expression Is Associated With Improved Overall Survival in High-Grade Serous Ovarian Carcinoma: An Ovarian Tumor Tissue Analysis Consortium Study. Weir, Ashley, Eun-Young Kang, Nicola S. Meagher, Gregg S. Nelson, Prafull Ghatage, Cheng-Han Lee, Marjorie J. Riggan, Aleksandra Gentry-Maharaj, Andy Ryan, Naveena Singh, Martin Widschwendter, Jennifer Alsop, Susan J. Ramus, et al. British Journal of Cancer, November.

INTACT (S/N1806): Phase III Randomized Trial of Concurrent Chemoradiotherapy With or Without Atezolizumab in Localized Muscle Invasive Bladder Cancer—Toxicity Update on First 213 Patients.Singh, P., J.A. Efstathiou, M. Plets, S.G. Jhavar, S. Delacroix, A. Tripathi, A. Gupta, S. Sachdev, A. Jani, A.N. Kirschner, C. Tangen, R. Bangs, M. Joshi, B.A. Costello, I.L. Thompson, F.Y. Feng, and S. Lerner. International Journal of Radiation Oncology, Biology, Physics 114 (3): S76–77.

Real-World Utilization of Radiation Therapy (RT) in Multiple Myeloma (MM): An Analysis of the Connect® MM Registry. Ballas, L.K., S. Ailawadhi, M. Narang, C.J. Gasparetto, H. Lee, J.W. Hardin, B.G.M. Durie, K. Toomey, J. Omel, L.I. Wagner, R. Abonour, H.R. Terebelo, P. Joshi, E. Yu, L. Liu, R.M. Rifkin, and S. Jagannath. International Journal of Radiation Oncology, Biology, Physics 114 (3): S133–34.

Recruitment and Retention Strategies for the Diabetes RElated to Acute Pancreatitis and Its Mechanisms Study: From the Type 1 Diabetes in Acute Pancreatitis Consortium. Yazici, Cemal, Anne-Marie Dyer, Darwin L. Conwell, Elham Afghani, Dana K. Andersen, Marina Basina, Melena D. Bellin, Leslie R. Boone, Anna Casu, Jeffrey J. Easler, Carla J. Greenbaum, Phil A. Hart, Christie Y. Jeon, Peter J. Lee, Shelby Meier, Georgios I. Papachristou, Nazia T. Raja-Khan, Zeb I. Saeed, Jose Serrano, Dhiraj Yadav, Evan L. Fogel, and Type 1 Diabetes in Acute Pancreatitis Consortium (T1DAPC). Pancreas 51 (6): 598–603.

Cardiology

Cardiovascular and Hepatic Disease Associations by Magnetic Resonance Imaging: A Retrospective Cohort Study. Kwan, Alan C., Nancy Sun, Matthew Driver, Patrick Botting, Jesse Navarrette, David Ouyang, Shehnaz K. Hussain, Mazen Noureddin, Debiao Li, Joseph E. Ebinger, Daniel S. Berman, and Susan Cheng. Frontiers in Cardiovascular Medicine 9: 1009474.

Long-Term Outcomes of Transcatheter Aortic Valve Replacement With the Lotus Valve vs CoreValve/EvolutR: A Secondary Analysis of the REPRISE III Randomized Clinical Trial. Rizik, David G., Vivek Rajagopal, Raj R. Makkar, Tanvir Bajwa, Neal S. Kleiman, Axel Linke, Dean J. Kereiakes, Ron Waksman, Vinod H. Thourani, Robert C. Stoler, Gregory J. Mishkel, Vijay S. Iyer, Maurice Buchbinder, Matthias Götberg, Henrik Bjursten, Dominic J. Allocco, and Michael J. Reardon. JAMA Network Open 5 (10): e2238792.

Opportunities and Challenges in Heart Rhythm Research: Rationale and Development of an Electrophysiology Collaboratory. Nguyen, Duy T., Kenneth C. Bilchick, Sanjiv M. Narayan, Mina K. Chung, Kevin L. Thomas, Kenneth R. Laurita, Marmar Vaseghi, Roopinder Sandhu, Mihail G. Chelu, Prince J. Kannankeril, Douglas L. Packer, David D. McManus, Atul Verma, Matthew Singleton, Khaldoun Tarakji, Sana M. Al-Khatib, Jonathan R. Kaltman, Ravi C. Balijepalli, George F. Van Hare, and Jodie L. Hurwitz. Heart Rhythm 19 (11): 1927–45.

Utility of Transesophageal Echocardiogram Surveillance After Watchman Device Placement. Wu, Stephanie, Harjit Minhas, Takahiro Shiota, Robert J. Siegel, and Florian Rader. Echocardiography (Mount Kisco, N.Y.), November.

Computational Biomedicine 

A Manifesto on Explainability for Artificial Intelligence in Medicine. 2022b. Combi, Carlo, Beatrice Amico, Riccardo Bellazzi, Andreas Holzinger, Jason H. Moore, Marinka Zitnik, and John H. Holmes. Artificial Intelligence in Medicine 133 (November): 102423.

Medicine

An Eight-Year, Single-Center Experience on Ultrasound Assisted Thrombolysis With Moderate-Dose, Slow-Infusion Regimen in Pulmonary Embolism. Kaymaz, Cihangir, Ozgur Yasar Akbal, Berhan Keskin, Hacer Ceren Tokgoz, Aykun Hakgor, Ali Karagoz, Seda Tanyeri, Barkın Kultursay, Seyhmus Kulahcioglu, Cem Dogan, Zubeyde Bayram, Süleyman Çağan Efe, Atakan Erkılınç, Ibrahim Halil Tanboga, Mehmet Akbulut, Nihal Ozdemir, Victor Tapson, and Stavros Konstantinides. Current Vascular Pharmacology 20 (4): 370–78.

Design, Implementation, and Evaluation of a Pharmacist-Led Outpatient Benzodiazepine Tapering Clinic. Gregorian, Tania, Kristin Bradley, Scott Campbell, Rachel Mashburn, Richard Beuttler, and Michelle S. Keller. Journal of the American Pharmacists Association, October.

Hermansky-Pudlak Syndrome Type 1 Causes Impaired Anti-Microbial Immunity and Inflammation Due to Dysregulated Immunometabolism. Cavounidis, Athena, Sumeet Pandey, Melania Capitani, Matthias Friedrich, Amy Cross, Lisa Gartner, Dominik Aschenbrenner, Seunghee Kim-Schulze, Ying Ka Lam, Georgina Berridge, Dermot P. B. McGovern, Benedikt Kessler, Roman Fischer, Paul Klenerman, Joanna Hester, Fadi Issa, Esther A. Torres, Fiona Powrie, Bernadette R. Gochuico, William A. Gahl, Louis Cohen, and Holm H. Uhlig. Mucosal Immunology, October.

Trans-Ancestry, Bayesian Meta-Analysis Discovers 20 Novel Risk Loci for Inflammatory Bowel Disease in an African American, East Asian, and European Cohort. Cordero, Roberto Y., Jennifer B. Cordero, Andrew B. Stiemke, Lisa W. Datta, Steven Buyske, Subra Kugathasan, Dermot P. B. McGovern, Steven R. Brant, and Claire L. Simpson. Human Molecular Genetics, October, ddac269.

Author Correction: Genome-Wide Association Study Identifies Sjögren’s Risk Loci With Functional Implications in Immune and Glandular Cells. Khatri, Bhuwan, Kandice L. Tessneer, Astrid Rasmussen, Farhang Aghakhanian, Tove Ragna Reksten, Adam Adler, Ilias Alevizos, Juan-Manuel Anaya, Lara A. Aqrawi, Eva Baecklund, Johan G. Brun, Sara Magnusson Bucher, Christopher J. Lessard, et al. Nature Communications 13 (1): 6519.

Impact of Belimumab on Organ Damage in Systemic Lupus Erythematosus. Urowitz, Murray B., Cynthia Aranow, Yumi Asukai, Damon L. Bass, Ian N. Bruce, Deven Chauhan, Maria Dall’Era, Richard Furie, Norma Lynn Fox, Jennifer A. Gilbride, Anne Hammer, Ellen M. Ginzler, Tania Gonzalez‐Rivera, Roger A. Levy, Joan T. Merrill, Holly Quasny, David A. Roth, William Stohl, Ronald van Vollenhoven, and Daniel J. Wallace. Arthritis Care & Research 74 (11): 1822–28.

Basal Cell-Derived WNT7A Promotes Fibrogenesis at the Fibrotic Niche in Idiopathic Pulmonary Fibrosis. Huang, Guanling, Jiurong Liang, Kevin Huang, Xue Liu, Forough Taghavifar, Changfu Yao, Tanyalak Parimon, Ningshan Liu, Kristy Dai, Adam Aziz, Yizhou Wang, Richard T. Waldron, Hongmei Mou, Barry Stripp, Paul W. Noble, and Dianhua Jiang. American Journal of Respiratory Cell and Molecular Biology, November.

Changes in Blood Pressure Outcomes Among Hypertensive Individuals During the COVID-19 Pandemic: A Time Series Analysis in Three US Healthcare Organizations. Gotanda, Hiroshi, Nadia Liyanage-Don, Andrew E. Moran, Marie Krousel-Wood, Jonas B. Green, Yiyi Zhang, and Teryl K. Nuckols. Hypertension (Dallas, Tex.: 1979), November.

Risk of Advanced Fibrosis in First-Degree Relatives of Patients With Nonalcoholic Fatty Liver Disease. Tamaki, Nobuharu, Noora Ahlholm, Panu K. Luukkonen, Kimmo Porthan, Suzanne R. Sharpton, Veeral Ajmera, Yuko Kono, Shravan Dave, Aijaz Ahmed, Vinay Sundaram, Michael J. Wilkinson, Heather Patton, Hersh Gupta, Vanessa Cervantes, Christie Hernandez, Scarlett J. Lopez, Ria Loomba, Amanda Baumgartner, Lisa Richards, Perttu Et Arkkila, Katriina Nemes, Helena Isoniemi, Hannele Yki-Järvinen, and Rohit Loomba. The Journal of Clinical Investigation 132 (21): e162513.

Treat-to-Target: The Era of Targeted Immunosuppressive Agents in IBD Management. Marino, Daniel, Siddharth Singh, Jason Hou, Corey Siegel, Gil Melmed, and Samir A. Shah. Rhode Island Medical Journal (2013) 105 (9): 25–29.

Clinical Outcomes Following Stereotactic Body Radiation Therapy (SBRT) for Non-Spinal Bone Metastases: A Systematic Review and Meta-Analysis. Valluri, A., R. Singh, E.J. Lehrer, Y. Cao, R. Upadhyay, D.M. Trifiletti, S.S. Lo, K.J. Redmond, A. Sahgal, and J.D. Palmer. International Journal of Radiation Oncology, Biology, Physics 114 (3): e437–e437.

Multi-Institutional Datasets Validate the Recursive Partitioning Analysis for Overall Survival in Patients Undergoing Spine Radiosurgery for Spine Metastasis. Balagamwala, E.H., A. Sahgal, D. Chapman, E.M. Schaff, F. Siddiqui, S.S. Lo, W. Wei, M. Campbell, J. Tsai, S.K. Schaub, L. Angelov, Z.S. Mayo, J.H. Suh, J. Hanan, and S.T. Chao. International Journal of Radiation Oncology, Biology, Physics114 (3): e86–87.

Prognostic Value of the Intermediate Risk Feature in Men With Favorable Intermediate Risk Prostate Cancer: Implications for Active Surveillance. Sherer, M., T.J. Nelson, P.T. Courtney, K. Guram, G. Rodrigues De Moraes, A. Bagrodia, and B.S. Rose. International Journal of Radiation Oncology, Biology, Physics 114 (3): e246–47.

Neurology

Aversive Memory Formation in Humans Involves an Amygdala-Hippocampus Phase Code. Costa, Manuela, Diego Lozano-Soldevilla, Antonio Gil-Nagel, Rafael Toledano, Carina R. Oehrn, Lukas Kunz, Mar Yebra, Costantino Mendez-Bertolo, Lennart Stieglitz, Johannes Sarnthein, Nikolai Axmacher, Stephan Moratti, and Bryan A. Strange. Nature Communications 13 (1): 6403.

OBGYN

Getting to the Root of the Risk-the Underpinnings of a Novel Set of Risk Factors for Pregnancies Conceived With Assisted Reproductive Technology. Schaub, Amelia, Margareta D. Pisarska, and Jessica L. Chan. Fertility & Sterility 118 (5): 904–5.

Uterine Necrosis During Pregnancy Following Exploratory Laparotomy. Hirsch, Anna, Rachel Newman, and Mariam Naqvi. BMJ Case Reports 15 (11): e252273.

Pathology

Pancreatoblastoma in Elderly Adults: Report of Two Patients. Kulak, Ozlem, Arsen Osipov, Andrew E. Hendifar, Nicholas N. Nissen, Brian K. Cox, Ralph H. Hruban, and Danielle A. Hutchings. International Journal of Surgical Pathology, October, 10668969221133348.

GATA3 Expression in Clear Cell Adenocarcinoma of the Lower Urinary Tract: A Potential Diagnostic Pitfall. Akgul, Mahmut, Robert Humble, Abdullah Osme, Servet Yuce, Elif N. Kocak, Parisa Najafzadeh, Ankur Sangoi, Niharika Pattnaik, Sourav Mishra, Shivani Sharma, Nada Shaker, Seema Kaushal, Manas Baisakh, Andrea R. Lightle, Bonnie L. Balzer, Guang-Qian Xiao, Gregory T. MacLennan, Adeboye O. Osunkoya, Anil Parwani, Liang Cheng, Andrew Bellizzi, and Sambit K. Mohanty. Diagnostic Pathology 17 (1): 87.

Pediatrics

Failure to Thrive in an 8-Month-Old Female: Answers. Kim, Romina, XinYi Ye, Pedro A. Sanchez-Lara, Dechu Puliyanda, Sanjeev Kumar, and Helen Pizzo. Pediatric Nephrology (Berlin, Germany), October.

Sustained Virologic Suppression Reduces HIV-1 DNA Proviral Levels and HIV Antibodies in Perinatally HIV-Infected Children Followed From Birth. Fuller, Trevon, Tara Kerin, Ruth Cortado, Maria de Lourdes Benamor Teixeira, Maria Isabel Fragoso da Silveira Gouvêa, Christianne Moreira, Maria Leticia Santos Cruz, José Henrique Pilotto, Ivete Gomes, Breno Santos, Tauí Rocha, Priya R. Soni, Esau Joao, Myung Shin-Sim, Yvonne Bryson, and Karin Nielsen-Saines. Viruses 14 (11): 2350.

The Clinical Spectrum of SMA-PME and in Vitro Normalization of Its Cellular Ceramide Profile. Lee, Michelle M., Graeme S. V. McDowell, Darryl C. De Vivo, Daniel Friedman, Samuel F. Berkovic, Maria Spanou, Argirios Dinopoulos, Katheryn Grand, Pedro A. Sanchez-Lara, Michelle Allen-Sharpley, Jodi Warman-Chardon, Alexander Solyom, Thierry Levade, Edward H. Schuchman, Steffany A. L. Bennett, David A. Dyment, and Toni S. Pearson. Annals of Clinical and Translational Neurology, November.

Radiation Oncology 

A Phase 1 Study of TAK-676, a Novel STING Agonist, Plus Pembrolizumab Following Radiation Therapy in Patients With Advanced Non–Small-Cell Lung Cancer (NSCLC), Triple-Negative Breast Cancer (TNBC), or Squamous-Cell Carcinoma of the Head and Neck (SCCHN). Gerber, N.K., S.J. Chmura, J.J. Luke, S.L. Shiao, R. Basho, W.T. Iams, D.B. Page, C. Li, R.C. Gregory, M.H. Shaw, K.H. Horn, J. Gibbs, V.A. Appleman, A. Berger, A.O. Abu-Yousif, N.B. Lineberry, K.F. Stumpo, A. Elfiky, and B. Cooper. International Journal of Radiation Oncology, Biology, Physics 114 (3): e40–e40.

Association of Cardiac Sub-Structure Radiation Dose With Bradyarrhythmias and Tachyarrhythmias After Lung Cancer Radiotherapy. Atkins, K.M., A. Nikolova, C.V. Guthier, D.S. Bitterman, D.E. Kozono, A. Nohria, and R.H. Mak. International Journal of Radiation Oncology, Biology, Physics 114 (3): S58–59.

Challenges and Solutions During the COVID Pandemic for Patient Retention and Physician Engagement in the Phase 3 ATLAS Study of Apalutamide Added to Androgen Deprivation Therapy (ADT) in High-Risk Localized or Locally Advanced Prostate Cancer (HRLPC). Sandler, H.M., N. Shore, D. Dearnaley, S.J. Freedland, M.R. Smith, R. Rosales, S.D. Brookman-May, A.P. Dicker, M.R. McKenzie, A. Bossi, A. Widmark, T. Wiegel, J. Martin, B. Miladinovic, F. Lefresne, M. Ciprotti, S.A. McCarthy, S.D. Mundle, B.F. Tombal, and F.Y. Feng. International Journal of Radiation Oncology, Biology, Physics 114 (3): e244–45.

Correlation of Left Anterior Descending Coronary Artery Radiation Dose With Major Adverse Cardiac Events and Feasibility of Coronary Artery Sparing Treatment Planning in Lung Cancer.Zhang, S.C., C. Gay, E. McKenzie, S. Kim, T. Polishchuk, B. Hargens, L. Semaan-Corbett, J. Bennett, S. A. Shahi Savandi, C. Soliz, H. Park, B. Hakimian, A.J. Mirhadi, M. Kamrava, S. Padda, A. Nikolova, R.H. Mak, and K.M. Atkins. International Journal of Radiation Oncology, Biology, Physics 114 (3): S40–S40.

Deep Learning-Based Automated Cardiac Sub-Structure Contouring With Dosimetric and Clinical Outcomes Validation. Guthier, C.V., E. McKenzie, R. Zeleznik, D.S. Bitterman, J.S. Bredfeldt, H. Aerts, K.M. Atkins, and R.H. Mak. International Journal of Radiation Oncology, Biology, Physics 114 (3): S46–47.

Derivation of a Modified Novel Pathologic Nodal Classification System for Non-Small Cell Lung Cancer. Nguyen, A.T., M. Luu, E.M. Chung, D.J. Lu, A. Mita, A.J. Mirhadi, K.M. Atkins, and Z.S. Zumsteg. International Journal of Radiation Oncology, Biology, Physics 114 (3): e385–e385.

Drivers of Medicare Spending: A 20-Year Review of Radiation Oncology Charges Allowed per Person as Compared to Other Specialties. Mokhtech, M., J.H. Laird, S. Maroongroge, P.A.S. Johnstone, C.A. Mantz, R.D. Ennis, H.M. Sandler, B. Falit, A.P. Dosoretz, and J.B. Yu. International Journal of Radiation Oncology, Biology, Physics 114 (3): S102–S102.

Efficacy of Bicalutamide Monotherapy in Prostate Cancer: A Network Meta-Analysis of 10 Randomized Trials. Baydoun, A., Y. Sun, H.M. Sandler, M. Bolla, A. Nabid, J.W. Denham, A.Y. Jia, N.G. Zaorsky, J. Garcia, J. Brown, W.C. Jackson, R.T. Dess, J.A. Efstathiou, F.Y. Feng, P. Maingon, A. Steigler, L. Souhami, A. Berlin, A.U. Kishan, and D.E. Spratt. International Journal of Radiation Oncology, Biology, Physics 114 (3): e211–12.

Improved Cone-Beam Reconstruction Using a Prior Breathing Motion Model. Lauria, M., K. Singhrao, J.H. Lewis, D. O’Connell, A. Santhanam, L.M. Naumann, P. Lee, and D. Low. International Journal of Radiation Oncology, Biology, Physics 114 (3): S88–S88.

Interpretable Predictive Modeling for Major Adverse Cardiac Events Following Lung Cancer Radiotherapy. Qiao, E.M., J. He, D.S. Bitterman, C.V. Guthier, A. Nikolova, A. Nohria, K.M. Atkins, and R.H. Mak. International Journal of Radiation Oncology, Biology, Physics 114 (3): S112–S112.

Left Anterior Descending Coronary Artery Radiation Dose Association With All-Cause Mortality in NRG Oncology Trial RTOG 0617. McKenzie, E., R. Zakariaee, S. Zhang, C.V. Guthier, B. Hakimian, A.J. Mirhadi, M. Kamrava, S. Padda, J.H. Lewis, A. Nikolova, R.H. Mak, and K.M. Atkins. International Journal of Radiation Oncology, Biology, Physics 114 (3): S58–S58.

Optimal Duration of Androgen Deprivation Therapy (ADT) With Definitive Radiotherapy for Prostate Cancer: An Individual Patient Data (IPD) Meta-Analysis From the International MARCAP Consortium.Zaorsky, N.G., Y. Sun, A. Nabid, A. Zapatero, M. Bolla, J.W. Denham, T.M. Pisansky, H.M. Sandler, J.A. Efstathiou, P. Maingon, A. Steigler, L. Souhami, N. Carrier, J. Armstrong, W.C. Jackson, A.Y. Jia, T.M. Ma, T. Romero, A.U. Kishan, and D.E. Spratt. International Journal of Radiation Oncology, Biology, Physics 114 (3): S68–69.

Outcomes Associated With the Use of Tissue Equivalent Bolus Tailored by Skin Involvement Status in Postmastectomy Radiotherapy: A Single-Blinded Randomized Clinical Trial. Sapienza Sr, L.G., A. Mattar, V.F. Calsavara, J.J. Thomas, C. Pellizzon, and G. Baiocchi. International Journal of Radiation Oncology, Biology, Physics 114 (3): S146–S146. 

Phagocytosis Checkpoint Blockade Overcomes Immunosuppression Triggered by Radiation Therapy and PD1 Inhibition. Nguyen, A.T., T.B. Dar, J. Viramontes, N.Y. Mevises, F. Nsole Biteghe, S. Stevens, K. Kershaw, M. De Simone, E. Ko, D.J. Lu, E.M. Chung, S.C. Zhang, K.M. Atkins, M. Kamrava, H.M. Sandler, J. Guarnerio, S. Knott, Z.S. Zumsteg, and S.L. Shiao. International Journal of Radiation Oncology, Biology, Physics 114 (3): S41–S41.

Phase III Trial of Dose Escalated Radiation Therapy and Standard Androgen Deprivation Therapy (ADT) vs. Dose Escalated Radiation Therapy and Enhanced ADT With TAK-700 for Men With High-Risk Prostate Cancer (NRG Oncology/RTOG 1115). Michaelson, D., J.J. Dignam, D.A. Hamstra, F. Bachand, V. Master, D.W. Bruner, M. Torres, P.J. Saylor, R.E. Wallace, N. Vapiwala, J.A. Efstathiou, M. Roach III, S.A. Rosenthal, A. Raben, S.C. Morgan, V.S. Kavadi, D.E. Spratt, J.M. Michalski, J. Rodgers, and H.M. Sandler. International Journal of Radiation Oncology, Biology, Physics 114 (3): S67–68.

Prostate Cancer Risk Stratification in NRG Oncology Phase III Randomized Trials Using Multi-Modal Deep Learning With Digital Histopathology. Tward, J.D., J. Zhang, A. Esteva, O. Mohamad, D. van der Wal, J. Simko, S. DeVries, H.C. Huang, E.M. Schaeffer, T.M. Morgan, H.A. Campbell, J. Monson, J. Wallace, M.J. Ferguson, J.P. Bahary, H.M. Sandler, D.E. Spratt, J. Rodgers, F.Y. Feng, and P.T. Tran. International Journal of Radiation Oncology, Biology, Physics 114 (3): S2–S2.

Recent Trends in Medicare Payments for Outpatient Cancer Care at the End of Life. Mantz, C.A., C.M. Yashar, G.K. Bajaj, and H.M. Sandler. International Journal of Radiation Oncology, Biology, Physics114 (3): S101–2.

RTOG/NRG 1115 Quality of Life of Phase III Dose Escalated Radiation Therapy (RT) and Standard Androgen Deprivation Therapy (ADT) With GnRH Agonist vs. Dose Escalated RT and ADT With GnRH Agonist and Orteronel (TAK-700) for Men With High-Risk Prostate. Bruner, D.W., S. Pugh, D. Michaelson, D.A. Hamstra, F. Bachand, V. Master, M. Torres, I.D. Kaplan, S.A. Rosenthal, M. Roach III, A. Raben, J.M. Michalski, V.S. Kavadi, M. Ferguson, S.C. Morgan, D.P. D’Souza, L. DeMora, H.M. Sandler, and B. Movsas. International Journal of Radiation Oncology, Biology, Physics 114 (3): e214–e214.

Trends and Disparities in Telehealth Utilization for Cancer Care During COVID-19. Chung, E.M., S. Kim, S.C. Zhang, A.T. Nguyen, D.J. Lu, K.M. Atkins, and M. Kamrava. International Journal of Radiation Oncology, Biology, Physics 114 (3): e131–32.

Rehabilitation Medicine

Family Communication Challenges of Adolescents and Young Adults With Li-Fraumeni Syndrome: Implications for Psychosocial Care. Rising, Camella J., Catherine Wilsnack, Patrick Boyd, Alix G. Sleight, Sadie P. Hutson, Payal P. Khincha, and Allison Werner-Lin. Patient Education & Counseling 105 (11): 3259–66.

Surgery

Quantitative Evaluation of Aerosol Generation During In-Office Flexible Laryngoscopy. Bastien, Amanda J., Kwame Wiredu, Andrew Y. Lee, Christiaan Rees, Mason T. Hinchcliff, and Joseph A. Paydarfar. JAMA Otolaryngology-- Head & Neck Surgery, October.