Faculty Publications: Oct. 20-Oct. 27

This week’s edition of Faculty Publications includes Cedars-Sinai studies that were published Oct. 20-Oct.27. If you have a published paper from this period that does not appear on this list, please contact Sue Marone, who will add it to next week’s collection.

Anesthesiology

Improving Residency Applicant Personal Statements by Decreasing Hired Contractor Involvement. Johnstone, Robert E., Manuel C. Vallejo, and Mark Zakowski. Journal of Graduate Medical Education 14 (5): 526–28.

Biomedical Sciences 

New Insights into the Epitranscriptomic Control of Pluripotent Stem Cell Fate. Che, Young Hyun, Hojae Lee, and Yong Jun Kim. Experimental & Molecular Medicine, October.

Modeling Cardiac SARS-CoV-2 Infection With Human Pluripotent Stem Cells. Rockwood, Sarah J., Madelyn Arzt, and Arun Sharma. Current Cardiology Reports, October.

Radiomics-Based Machine Learning Approach in Differentiating Fibro-Adipose Vascular Anomaly From Venous Malformation. Dong, Jian, Yubin Gong, Qiuyu Liu, Yaping Wu, Fangfang Fu, Hui Han, Xiaochen Li, Changxian Dong, and Meiyun Wang. Pediatric Radiology, October.

Cancer

Mechanism of Sex Differences in Bladder Cancer: Evident and Elusive Sex-Biasing Factors. Lam, Christa M., Zihai Li, Dan Theodorescu, and Xue Li. Bladder Cancer (Amsterdam, Netherlands) 8 (3): 241–54.

A Phase II Study of Sapanisertib (TAK-228) a MTORC1/2 Inhibitor in Rapalog-Resistant Advanced Pancreatic Neuroendocrine Tumors (PNET): ECOG-ACRIN EA2161. Rajdev, Lakshmi, Ju-Whei Lee, Steven K. Libutti, Al B. Benson, George A. Fisher, Pamela L. Kunz, Andrew E. Hendifar, Paul Catalano, and Peter J. O’Dwyer. Investigational New Drugs, October.

Evaluation of the Toxicity of Caralluma Europaea (C.E) Extracts and Their Effects on Apoptosis and Chemoresistance in Pancreatic Cancer Cells. Amrati, Fatima Ez-Zahra, Omer Hany Miligy Elmadbouh, Mohamed Chebaibi, Badr Soufi, Raffaele Conte, Meryem Slighoua, Asmaa Saleh, Omkulthom Al Kamaly, Aziz Drioiche, Touria Zair, Mouad Edderkaoui, and Dalila Bousta. Journal of Biomolecular Structure & Dynamics, October, 1–18.

Distinct Germline Genetic Susceptibility Profiles Identified for Common Non-Hodgkin Lymphoma Subtypes. Berndt, Sonja I., Joseph Vijai, Yolanda Benavente, Nicola J. Camp, Alexandra Nieters, Zhaoming Wang, Karin E. Smedby, Geffen Kleinstern, Henrik Hjalgrim, Caroline Besson, Christine F. Skibola, Lindsay M. Morton, Nathaniel Rothman, et al. Leukemia, October.

Combination of the STING Agonist MIW815 and PD-1 Inhibitor Spartalizumab in Advanced/Metastatic Solid Tumors or Lymphomas: An Open-Label, Multicenter, Phase Ib Study. Meric-Bernstam, Funda, Randy F. Sweis, Stefan Kasper, Omid Hamid, Shailender Bhatia, Reinhard Dummer, Agostina Stradella, Georgina V. Long, Anna Spreafico, Toshio Shimizu, Neeltje Steeghs, Jason J. Luke, Sarah M. McWhirter, Thomas Müller, Nitya Nair, Nancy Lewis, Xinhui Chen, Andrew Bean, Lisa Kattenhorn, Marc Pelletier, and Shahneen Sandhu. Clinical Cancer Research, October, CCR-22-2235.

Cardiac Surgery 

Editors’ Choice: Challenges of Randomized Trials of Cardiothoracic Surgery. Mitzman, Brian, and Joanna Chikwe. The Annals of Thoracic Surgery 114 (5): 1531–33.

Cardiology

Immune and Inflammatory Mechanisms of Abdominal Aortic Aneurysm. Márquez-Sánchez, Ana Cristina, and Ekaterina K. Koltsova. Frontiers in Immunology 13: 989933.

2022 AHA/ACC Key Data Elements and Definitions for Cardiovascular and Noncardiovascular Complications of COVID-19: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Data Standards. Writing Committee Members, Biykem Bozkurt, Sandeep R. Das, Daniel Addison, Aakriti Gupta, Hani Jneid, Sadiya S. Khan, George Augustine Koromia, Prathit A. Kulkarni, Kathleen LaPoint, Eldrin F. Lewis, Erin D. Michos, Pamela N. Peterson, Mohit K. Turagam, Tracy Y. Wang, and Clyde W. Yancy. Journal of the American College of Cardiology 80 (4): 388–465.

Substantial Fat Loss in Physique Competitors Is Characterized by Increased Levels of Bile Acids, Very-Long Chain Fatty Acids, and Oxylipins. Sarin, Heikki V., Juha J. Hulmi, Youwen Qin, Michael Inouye, Scott C. Ritchie, Susan Cheng, Jeramie D. Watrous, Thien-Tu C. Nguyen, Joseph H. Lee, Zhezhen Jin, Joseph D. Terwilliger, Teemu Niiranen, Aki Havulinna, Veikko Salomaa, Kirsi H. Pietiläinen, Ville Isola, Juha P. Ahtiainen, Keijo Häkkinen, Mohit Jain, and Markus Perola. Metabolites 12 (10): 928.

Sudden Cardiac Death in Patients With Type 1 Versus Type 2 Diabetes. Norby, Faye L., Kyndaron Reinier, Audrey Uy-Evanado, Gregory A. Nichols, Eric C. Stecker, Jonathan Jui, and Sumeet S. Chugh. Mayo Clinic Proceedings, October, S0025-6196(22)00309-3.

Imaging

Intergenerational Neuroimaging Study: Mother-Infant Functional Connectivity Similarity and the Role of Infant and Maternal Factors. Kim, Pilyoung, Haitao Chen, Alexander J. Dufford, Rebekah Tribble, John Gilmore, and Wei Gao. Cerebral Cortex (New York, N.Y.: 1991) 32 (15): 3175–86.

Deep Learning of Coronary Calcium Scores From PET/CT Attenuation Maps Accurately Predicts Adverse Cardiovascular Events. Pieszko, Konrad, Aakash Shanbhag, Aditya Killekar, Robert J. H. Miller, Mark Lemley, Yuka Otaki, Ananya Singh, Jacek Kwiecinski, Heidi Gransar, Serge D. Van Kriekinge, Paul B. Kavanagh, Edward J. Miller, Timothy Bateman, Joanna X. Liang, Daniel S. Berman, Damini Dey, and Piotr J. Slomka. JACC. Cardiovascular Imaging, August, S1936-878X(22)00395-3.

The Effect of Patient and Imaging Characteristics on Coronary CT Angiography Assessed Pericoronary Adipose Tissue Attenuation and Gradient. Boussoussou, Melinda, Borbála Vattay, Bálint Szilveszter, Judit Simon, Andrew Lin, Milán Vecsey-Nagy, Gábor Konkoly, Béla Merkely, Pál Maurovich-Horvat, Damini Dey, and Márton Kolossváry. Journal of Cardiovascular Computed Tomography, October, S1934-5925(22)00281-7.

Association between Hypercholesterolemia and Mortality Risk Among Patients Referred for Cardiac Imaging Test: Evidence of a ‘Cholesterol Paradox?’ Rozanski, Alan, Donghee Han, Michael J. Blaha, Heidi Gransar, John Friedman, Sean Hayes, Louise E. J. Thomson, Michael D. Miedema, Khurram Nasir, Matthew J. Budoff, Leslee J. Shaw, John A. Rumberger, Roger S. Blumenthal, Todd Villines, Fay Lin, and Daniel S. Berman. Progress in Cardiovascular Diseases, October, S0033-0620(22)00106-2.

Calcium Scoring in Low-Dose Ungated Chest CT Scans Using Convolutional Long-Short Term Memory Networks. Pieszko, K., A. Shanbhag, A. Killekar, M. Lemley, Y. Otaki, Serge Van Kriekinge, Paul Kavanagh, Robert Jh Miller, Edward J. Miller, Tim Bateman, D. Dey, D. Berman, and P. Slomka. Proceedings of SPIE--the International Society for Optical Engineering 12032 (March): 120323A.

Direct Risk Assessment From Myocardial Perfusion Imaging Using Explainable Deep Learning. Singh, Ananya, Robert J. H. Miller, Yuka Otaki, Paul Kavanagh, Michael T. Hauser, Evangelos Tzolos, Jacek Kwiecinski, Serge Van Kriekinge, Chih-Chun Wei, Tali Sharir, Andrew J. Einstein, Mathews B. Fish, Terrence D. Ruddy, Philipp A. Kaufmann, Albert J. Sinusas, Edward J. Miller, Timothy M. Bateman, Sharmila Dorbala, Marcelo Di Carli, Joanna X. Liang, Cathleen Huang, Donghee Han, Damini Dey, Daniel S. Berman, and Piotr J. Slomka. JACC. Cardiovascular Imaging, October, S1936-878X(22)00484-3.

Medicine

Regulatory Network and Interplay of Hepatokines, Stellakines, Myokines and Adipokines in Nonalcoholic Fatty Liver Diseases and Nonalcoholic Steatohepatitis. Yang, Bing, Liqing Lu, Dongmei Zhou, Wei Fan, Lucía Barbier-Torres, Justin Steggerda, Heping Yang, and Xi Yang. Frontiers in Endocrinology13: 1007944.

Most Excess Years of Potential Life Loss Among Individuals With Cirrhosis During the Pandemic Were Not Related to COVID-19. Zhao, Yunyu, Yee Hui Yeo, Jamil Samaan, Fan Lv, Xinyuan He, Ning Gao, Justin Park, Ju Dong Yang, Walid Ayoub, Michelle C. Odden, Fanpu Ji, and Mindie H. Nguyen. Gut, September, gutjnl-2022-328188.

Health Information Use by Patients With Systemic Lupus Erythematosus (SLE) Pre and During the COVID-19 Pandemic. Cardwell, Francesca S., Susan J. Elliott, Ricky Chin, Yvan St Pierre, May Y. Choi, Murray B. Urowitz, Guillermo Ruiz-Irastorza, Sasha Bernatsky, Daniel J. Wallace, Michelle A. Petri, Susan Manzi, Sang-Cheol Bae, Jung-Min Shin, Anselm Mak, Jiacai Cho, Christine A. Peschken, Rosalind Ramsey-Goldman, Paul R. Fortin, John G. Hanly, Bernardo A. Pons-Estel, Romina Nieto, Anca D. Askanase, Juanita Romero-Diaz, Marta Mosca, Ian N. Bruce, Leigha Rowbottom, Leanne Mielczarek, Karin Tse, Ashley Marion, Juan Carlos Cáhiz-González, Teresa G. Cattoni, Alain Cornet, and Ann Elaine Clarke. Lupus Science & Medicine 9 (1): e000755.

Effect of Obesity on Risk of Hospitalization, Surgery, and Serious Infection in Biologic-Treated Patients With Inflammatory Bowel Diseases: A CA-IBD Cohort Study. Gu, Phillip, Jiyu Luo, Jihoon Kim, Paulina Paul, Berkeley Limketkai, Jenny S. Sauk, Sunhee Park, Nimisha Parekh, Kai Zheng, Vivek Rudrapatna, Gaurav Syal, Christina Ha, Dermot P. McGovern, Gil Y. Melmed, Phillip Fleshner, Samuel Eisenstein, Sonia Ramamoorthy, Parambir S. Dulai, Brigid S. Boland, Eduardo Grunvald, Uma Mahadevan, Lucila Ohno-Machado, William J. Sandborn, and Siddharth Singh. The American Journal of Gastroenterology 117 (10): 1639–47.

Combination Therapy With Immunomodulators Improves the Pharmacokinetics of Infliximab but not Vedolizumab or Ustekinumab. Yarur, Andres J., Dermot McGovern, Maria T. Abreu, Adam Cheifetz, Konstantinos Papamichail, Parakkal Deepak, Alexandra Bruss, Poonam Beniwal-Patel, Marla Dubinsky, Stephan R. Targan, and Gil Y. Melmed. Clinical Gastroenterology and Hepatology, October, S1542-3565(22)01005-9.

The Relationship Between Lifetime Exposure to Potentially Traumatic Events, Peritraumatic Dissociation, and PTSD in a Sample of Sexually Assaulted Women in Sao Paulo, Brazil. Zylberstajn, Cecilia, Bruno Messina Coimbra, Thauana T. Oliveira-Watanabe, Mariana Rangel Maciel, Vinicius F. Calsavara, Miranda Olff, Marcelo Feijo Mello, and Andrea Feijo Mello. Journal of Trauma & Dissociation, October, 1–16.

TGF-β Controls Stromal Telomere Length through Epigenetic Modifications. Mishra, Rajeev, Subhash Haldar, Shea Biondi, Vikash Kumar Bhari, Gyanendra Singh, and Neil A. Bhowmick. 3 Biotech 12 (11): 290.

Neurology

An Update on Diagnostic Laboratory Biomarkers for Multiple Sclerosis. Kaisey, Marwa, Ghazal Lashgari, Justyna Fert-Bober, Daniel Ontaneda, Andrew J. Solomon, and Nancy L. Sicotte. Current Neurology and Neuroscience Reports, October.

Orthopaedics

Platelet-Rich Plasma Use for Hip and Knee Osteoarthritis in the United States. Li, Alan K., Alexandra I. Stavrakis, and Christos Photopoulos. The Knee 39 (October): 239–46.

Pathology

Ensuring Remote Diagnostics for Pathologists: An Open Letter to the US Congress. Lennerz, Jochen K., Liron Pantanowitz, Mitual B. Amin, Isam-Eldin Eltoum, Meera R. Hameed, Alexana N. Kalof, Elham Khanafshar, Lakshmi P. Kunju, Audrey J. Lazenby, Kathleen T. Montone, Christopher N. Otis, Michelle D. Reid, Erika R. Bracamonte, et al. Nature Medicine, October.

Pediatrics

The Changing Epidemiology of PIMS-TS across COVID-19 Waves: Prospective National Surveillance, January 2021 to July 2022, England. Shingleton, Joseph, Hannah Williams, Godwin Oligbu, Annabel Powell, Jonathan Cohen, Moshe Arditi, Tiffany Watson-Koszel, Simon Kenny, Nick Gent, and Shamez N. Ladhani. The Journal of Infection, October, S0163-4453(22)00617-X.

Temporary Internal Distraction for Severe Scoliosis: Two-Year Minimum Follow-Up. Badin, Daniel, Arjun Gupta, David L. Skaggs, and Paul D. Sponseller. Spine Deformity, October.

Radiation Oncology 

Sequencing of Androgen-Deprivation Therapy of Short Duration With Radiotherapy for Nonmetastatic Prostate Cancer (SANDSTORM): A Pooled Analysis of 12 Randomized Trials. Ma, Ting Martin, Yilun Sun, Shawn Malone, Mack Roach, David Dearnaley, Thomas M. Pisansky, Felix Y. Feng, Howard M. Sandler, Jason A. Efstathiou, Isabel Syndikus, Emma C. Hall, Alison C. Tree, Matthew R. Sydes, Claire Cruickshank, Soumyajit Roy, Michel Bolla, Philippe Maingon, Theo De Reijke, Abdenour Nabid, Nathalie Carrier, Luis Souhami, Almudena Zapatero, Araceli Guerrero, Ana Alvarez, Carmen Gonzalez San-Segundo, Xavier Maldonado, Tahmineh Romero, Michael L. Steinberg, Luca F. Valle, Matthew B. Rettig, Nicholas G. Nickols, Jonathan E. Shoag, Robert E. Reiter, Nicholas G. Zaorsky, Angela Y. Jia, Jorge A. Garcia, Daniel E. Spratt, Amar U. Kishan, and Meta-Analysis of Randomized Trials in Cancer of the Prostate (MARCAP) Consortium Investigators. Journal of Clinical Oncology, October, JCO2200970.

Surgery

Procedures Never Explained in Textbooks: How to Correctly Convert a Closed-Suction Drain to a Closed-Gravity Drain, and How to Correctly Remove a Closed-Suction Drain Off Suction. Stelmar, Jenna, Shannon M. Smith, Andrew Chen, John M. Masterson, Vivian Hu, and Maurice M. Garcia. Journal of Surgery and Research 5 (3): 419–22.

Hartmann’s Reversal Is Associated With Worse Outcomes Compared to Elective Left Colectomy: A NSQIP Analysis of 36,794 Cases. Nasseri, Yosef, Andy Liu, Eli Kasheri, Kimberly Oka, Sean Langenfeld, Abbas Smiley, Jason Cohen, Joshua Ellenhorn, and Moshe Barnajian. American Journal of Surgery, October, S0002-9610(22)00656-0.

Blocking Autophagy in M1 Macrophages Enhances Virus Replication and Eye Disease in Ocularly Infected Transgenic Mice. Jaggi, Ujjaldeep, Harry H. Matundan, Dhong Hyun Lee, and Homayon Ghiasi. Journal of Virology, October, e0140122.