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Faculty Publications: Oct. 13-Oct. 20

A Comprehensive Digest of Research Publications From Cedars-Sinai Investigators

This week’s edition of Faculty Publications includes Cedars-Sinai studies that were published Oct. 13-Oct. 20. If you have a published paper from this period that does not appear on this list, please contact Sue Marone, who will add it to next week’s collection.


Adverse Effects Associated With Patient-Controlled Analgesia With Ketamine Combined With Opioids and Ketamine Infusion With PCA Bolus in Postoperative Spine Patients: A Retrospective Review. Pouldar, Tiffany M., Dermot P. Maher, Alexander W. Betz, Jeffrey J. Wiegers, Jeremy A. Friedman, Sameer S. Zaidi, Ali Rejali, Hai P. Tran, Roya Yumul, and Charles Louy. Journal of Pain Research 15: 3127–35.


Current Gaps and Opportunities in Screening, Prevention, and Treatment of Cervical Cancer. Rimel, Bobbie J., Charles A. Kunos, Nikeya Macioce, and Sarah M. Temkin. Cancer, October.

Comparison of Simple-Summated Scoring and Toxicity Index Scoring of Symptom Bother in the NSABP B-30 Clinical Trial. Hays, Ron D., Gillian Gresham, Patricia A. Ganz, and Mourad Tighiouart. Applied Research in Quality of Life, September.

Exceptional Response to Erdafitinib in FGFR2-Mutated Metastatic Pancreatic Ductal Adenocarcinoma. Ng, Camille F., John Glaspy, Veronica R. Placencio-Hickok, Shant Thomassian, Jun Gong, Arsen Osipov, Andrew E. Hendifar, and Natalie Moshayedi. Journal of the National Comprehensive Cancer Network: JNCCN20 (10): 1076–79.

FOXC2 Promotes Vasculogenic Mimicry in Ovarian Cancer. Recouvreux, Maria Sol, Jiangyong Miao, Maricel C. Gozo, Jingni Wu, Ann E. Walts, Beth Y. Karlan, and Sandra Orsulic. Cancers 14 (19): 4851.

Clinical and Molecular Response to Tebentafusp in Previously Treated Patients With Metastatic Uveal Melanoma: A Phase 2 Trial. Carvajal, Richard D., Marcus O. Butler, Alexander N. Shoushtari, Jessica C. Hassel, Alexandra Ikeguchi, Leonel Hernandez-Aya, Paul Nathan, Omid Hamid, Josep M. Piulats, Matthew Rioth, Douglas B. Johnson, Jason J. Luke, Enrique Espinosa, Serge Leyvraz, Laura Collins, Howard M. Goodall, Koustubh Ranade, Chris Holland, Shaad E. Abdullah, Joseph J. Sacco, and Takami Sato. Nature Medicine, October.

Derivation and External Validation of Machine Learning-Based Model for Detection of Pancreatic Cancer. Chen, Wansu, Yichen Zhou, Fagen Xie, Rebecca K. Butler, Christie Y. Jeon, Tiffany Q. Luong, Botao Zhou, Yu-Chen Lin, Eva Lustigova, Joseph R. Pisegna, Sungjin Kim, and Bechien U. Wu. The American Journal of Gastroenterology, October.

Does Race Make a Difference in How Long Men With Advanced Prostate Cancer Live When Treated With Abiraterone or Enzalutamide? George, Daniel J., Krishnan Ramaswamy, Ahong Huang, David Russell, Neil M. Schultz, Nora Janjan, and Stephen J. Freedland. Future Oncology (London, England), October.

ASO Author Reflections: The Evolution of Axillary Management in Breast Cancer. Schwartz, Theresa, Ashley D. Marumoto, and Armando E. Giuliano. Annals of Surgical Oncology, October.

Simulation Study Comparing Analytical Methods for Single-Item Longitudinal Patient-Reported Outcomes Data. Calsavara, Vinicius F., Márcio A. Diniz, Mourad Tighiouart, Patricia A. Ganz, N. Lynn Henry, Ron D. Hays, Greg Yothers, and André Rogatko. Quality of Life Research: An International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation, October.

The 5-Hydroxymethylcytosine Landscape of Prostate Cancer. Sjöström, Martin, Shuang G. Zhao, Samuel Levy, Meng Zhang, Yuhong Ning, Raunak Shrestha, Arian Lundberg, Cameron Herberts, Adam Foye, Rahul Aggarwal, Junjie T. Hua, Haolong Li, Felix Y. Feng, et al. Cancer Research, October, OF1–15.

A Randomized Study of Temozolomide or Temozolomide and Capecitabine in Patients With Advanced Pancreatic Neuroendocrine Tumors (ECOG-ACRIN E2211). Kunz, Pamela L., Noah T. Graham, Paul J. Catalano, Halla S. Nimeiri, George A. Fisher, Teri A. Longacre, Carlos J. Suarez, Brock A. Martin, James C. Yao, Matthew H. Kulke, Andrew E. Hendifar, James C. Shanks, Manisha H. Shah, Mark M. Zalupski, Edmond L. Schmulbach, Diane L. Reidy-Lagunes, Jonathan R. Strosberg, Peter J. O’Dwyer, and Al B. Benson. Journal of Clinical Oncology, October, 101200JCO2201013.

Plant-Based Diets to Reduce Prostate Cancer Risk and Improve Prostate Cancer Outcomes-Ready for Prime Time? Friedrich, Nadine A., Stephen J. Freedland, and Ilona Csizmadi. Prostate Cancer and Prostatic Diseases, October.


Cold Pressor Testing and Sympathetic Nervous System Contribution to Ischemia With No Obstructive Coronary Artery Disease: Results from the Women’s Ischemia Syndrome Evaluation-Coronary Vascular Dysfunction Project. Wei, J., L. L. Barsky, S. Jalnapurkar, P. Zarrini, G. Cook-Wiens, A. AlBadri, M. D. Nelson, C. Shufelt, B. Sharif, D. S. Berman, Lej Thomson, E. M. Handberg, J. W. Petersen, R. D. Anderson, C. J. Pepine, C. N. Bairey Merz, and P. K. Mehta. American Heart Journal Plus: Cardiology Research and Practice 13 (January): 100080.

Premature Menopause and Cardiovascular Disease: Can We Blame Estrogen? Torbati, Tina, Chrisandra Shufelt, Janet Wei, and C. Noel Bairey Merz. European Heart Journal, August, ehac321.

The Effects of Device-Based Cardiac Contractility Modulation Therapy on Left Ventricle Global Longitudinal Strain and Myocardial Mechano-Energetic Efficiency in Patients With Heart Failure With Reduced Ejection Fraction. Masarone, Daniele, Michelle M. Kittleson, Stefano De Vivo, Antonio D’Onofrio, Ernesto Ammendola, Gerardo Nigro, Carla Contaldi, Maria L. Martucci, Vittoria Errigo, and Giuseppe Pacileo. Journal of Clinical Medicine 11 (19): 5866.

Managing Heart Failure in Patients on Dialysis: State-of-the-Art Review. Khan, Muhammad Shahzeb, Aymen Ahmed, Stephen J. Greene, Mona Fiuzat, Michelle M. Kittleson, Javed Butler, George L. Bakris, and Gregg C. Fonarow. Journal of Cardiac Failure, October, S1071-9164(22)00730-8.

Cannabis Use and Heart Transplantation: Disparities and Opportunities to Improve Outcomes. Ilonze, Onyedika J., Denise C. Vidot, Khadijah Breathett, Marlene Camacho-Rivera, Subha V. Raman, Jon A. Kobashigawa, and Larry A. Allen. Circulation. Heart Failure, October, e009488.

The Impact of the United Network of Organ Sharing Allocation Change on Waitlist Trajectories of Inpatients Listed With Inotropic Support: A Single-Center Analysis. Cao, Louie, Seong Kyu Kim, Brandon Schwartz, Robert Cole, Jignesh Patel, Lawrence Czer, Fardad Esmailian, Jon A. Kobashigawa, Michele A. Hamilton, and Michelle M. Kittleson. Clinical Transplantation, October, e14834.


Machine Learning From Quantitative Coronary Computed Tomography Angiography Predicts Fractional Flow Reserve-Defined Ischemia and Impaired Myocardial Blood Flow. Lin, Andrew, Pepijn A. van Diemen, Manish Motwani, Priscilla McElhinney, Yuka Otaki, Donghee Han, Alan Kwan, Evangelos Tzolos, Eyal Klein, Keiichiro Kuronuma, Kajetan Grodecki, Benjamin Shou, Richard Rios, Nipun Manral, Sebastien Cadet, Ibrahim Danad, Roel S. Driessen, Daniel S. Berman, Bjarne L. Nørgaard, Piotr J. Slomka, Paul Knaapen, and Damini Dey. Circulation. Cardiovascular Imaging 15 (10): e014369.

Changes in Metabolic Syndrome Burden and Risk of Coronary Artery Calcification Progression in Statin-Naïve Young Adults. Ahn, Hyo-Jeong, Heesun Lee, Hyo Eun Park, Donghee Han, Hyuk-Jae Chang, Eun Ju Chun, Hae-Won Han, Jidong Sung, Hae Ok Jung, and Su-Yeon Choi. Atherosclerosis 360 (October): 27–33.

Comparison of Outcomes of Invasive or Conservative Management of Chronic Coronary Disease in Four Randomized Controlled Trials. Mavromatis, Kreton, William E. Boden, David J. Maron, G. B. John Mancini, William S. Weintraub, Gilbert Gosselin, Daniel S. Berman, Leslee J. Shaw, John A. Spertus, and Judith S. Hochman. The American Journal of Cardiology, October, S0002-9149(22)01002-5.

Who Should Be Referred for a CT Coronary Calcium Score? Introducing a Simple Patient Risk Questionnaire Combining Traditional and Novel Risk Factors. Fenton, Stephen M., Millie Arora, Heidi Gransar, Daniel S. Berman, and Nathan D. Wong. Coronary Artery Disease, October.


Current Perspectives on Pediatric Inflammatory Bowel Disease Focusing on Transitional Care Management. What Should We Consider? Constanza Bay, M., F. Paulina Núñez, Rodrigo Quera, and Andrés J. Yarur. Gastroenterologia Y Hepatologia, October, S0210-5705(22)00229-1.

Expert Panel Consensus on Clinical Assertion Statements Describing Noninvasive Tools for Diagnosing Nonalcoholic Steatohepatitis. Jacobson, Ira M., Vincent Wai-Sun Wong, Laurent Castera, Quentin M. Anstee, Mazen Noureddin, Kenneth Cusi, Stephen A. Harrison, Elisabetta Bugianesi, and Zobair M. Younossi. Journal of Clinical Gastroenterology, October.

Bile Acid and Gut Microbiota in Irritable Bowel Syndrome. Min, Yang Won, Ali Rezaie, and Mark Pimentel. Journal of Neurogastroenterology and Motility 28 (4): 549–61.


Diagnosis of Chronic Inflammatory Demyelinating Polyneuropathy. Allen, Jeffrey A., and Richard A. Lewis. Muscle & Nerve 66 (5): 545–51.


Regional Variation in Hormonal and Metabolic Parameters of White and Black Women With PCOS in the United States. VanHise, Katherine, Jessica L. Chan, Sahar Wertheimer, Roy G. Handelsman, Ekaterina Clark, Rae Buttle, Erica T. Wang, Ricardo Azziz, and Margareta D. Pisarska. The Journal of Clinical Endocrinology and Metabolism, October, dgac515.

Maternal Anxiety, Depression and Stress Affects Offspring Gut Microbiome Diversity and Bifidobacterial Abundances. Galley, Jeffrey D., Lauren Mashburn-Warren, Lexie C. Blalock, Christian L. Lauber, Judith E. Carroll, Kharah M. Ross, Calvin Hobel, Mary Coussons-Read, Christine Dunkel Schetter, and Tamar L. Gur. Brain, Behavior, and Immunity, October, S0889-1591(22)00410-X.


Aqueous Skin Antisepsis Before Surgical Fixation of Open Fractures (Aqueous-PREP): A Multiple-Period, Cluster-Randomised, Crossover Trial. PREP-IT Investigators. Lancet (London, England) 400 (10360).

Many-Faceted Rasch Calibration of the Foot Function Index-Revised Short Form. Ryu, Seungho, Madeline P. Casanova, Jonathan D. Moore, Adam C. Cady, and Russell T. Baker. Journal of Foot and Ankle Research 15 (1): 77.


Creatine Supplementation Enhances Immunological Function of Neutrophils by Increasing Cellular Adenosine Triphosphate. Saito, Suguru, Duo-Yao Cao, Alato Okuno, Xiaomo Li, Zhenzi Peng, Musin Kelel, and Noriko M. Tsuji. Bioscience of Microbiota, Food and Health 41 (4): 185–94.


Cellular Shape Reinforces Niche to Stem Cell Signaling in the Small Intestine. Pentinmikko, Nalle, Rodrigo Lozano, Sandra Scharaw, Simon Andersson, Johanna I. Englund, David Castillo-Azofeifa, Aaron Gallagher, Martin Broberg, Ki-Young Song, Agustín Sola Carvajal, Alessondra T. Speidel, Michael Sundstrom, Nancy Allbritton, Molly M. Stevens, Ophir D. Klein, Ana Teixeira, and Pekka Katajisto. Science Advances 8 (41): eabm1847.


Standards of Care for the Health of Transgender and Gender Diverse People, Version 8. Coleman, E., A. E. Radix, W. P. Bouman, G. R. Brown, A. L. C. de Vries, M. B. Deutsch, R. Ettner, L. Fraser, M. Goodman, J. Green, A. B. Hancock, T. W. Johnson, J. Arcelus, et al. International Journal of Transgender Health 23 (Suppl 1): S1–259.

Differential Modulation of Cancer-Related Genes by Mitochondrial DNA Haplogroups and the STING DNA Sensing System. Schneider, Kevin, Marilyn Chwa, Shari R. Atilano, Sonali Nashine, Nitin Udar, David S. Boyer, S. Michal Jazwinski, Michael V. Miceli, Anthony B. Nesburn, Baruch D. Kuppermann, and M. Cristina Kenney. FASEB BioAdvances 4 (10): 675–89.

Toward Drainless Breast Reconstruction: A Pilot Study. Patel, Harsh, David Kulber, and Edward Ray. Plastic and Reconstructive Surgery. Global Open 10 (10): e4560.

Eerie ENT Cases Course Co-Directors’ Introduction. Hopp, Martin L., and Anca M. Barbu. Ear, Nose, & Throat Journal, October, 1455613221116222.