Los Angeles,
07:30 AM

Faculty Publications: July 28-August 4

A Comprehensive Digest of Research Publications From Cedars-Sinai Investigators

This week’s edition of Faculty Publications includes Cedars-Sinai studies that were published July 28-August 4. If you have a published paper from this period that does not appear on this list, please contact Sue Marone, who will add it to next week’s collection.


Cooled and Traditional Thermal Radiofrequency Ablation of Genicular Nerves in Patients With Chronic Knee Pain: A Comparative Outcomes Analysis. Wu, Bernie P., Daniel Grits, Victor Foorsov, Jijun Xu, Pavan Tankha, and Robert B. Bolash. Regional Anesthesia and Pain Medicine, August, rapm-2022-103693.


Aberrant Androgen Action in Prostatic Progenitor Cells Induces Oncogenesis and Tumor Development through IGF1 and Wnt Axes. Kim, Won Kyung, Adam W. Olson, Jiaqi Mi, Jinhui Wang, Dong-Hoon Lee, Vien Le, Alex Hiroto, Joseph Aldahl, Christian H. Nenninger, Alyssa J. Buckley, Robert Cardiff, Sungyong You, and Zijie Sun. Nature Communications 13 (1): 4364. 

Acute and Chronic Effects of Adjuvant Therapy on Inflammatory Markers in Breast Cancer Patients. Bower, Julienne E., Patricia A. Ganz, Michael R. Irwin, Steve W. Cole, Judith Carroll, Kate R. Kuhlman, Laura Petersen, Deborah Garet, Arash Asher, Sara A. Hurvitz, and Catherine M. Crespi. JNCI Cancer Spectrum, July, pkac052.

A Common Infrastructure for Real-World Patient-Reported Symptoms: One Size Fits Many. Hurk, Corina J. G. van den, Stephen T. Sonis, and Joel B. Epstein. Supportive Care in Cancer, July.

ASO Visual Abstract: Expanding Staging Criteria in T1-2N0 Hormone Receptor-Positive Breast Cancer Patients Enrolled in TAILORx. Kantor, Olga, Harold J. Burstein, Tari A. King, Steven Shak, Christy A. Russell, Armando E. Giuliano, Gabriel N. Hortobagyi, Eric P. Winer, Larissa A. Korde, Joseph A. Sparano, and Elizabeth A. Mittendorf. Annals of Surgical Oncology, July.

ASO Visual Abstract: Practice Patterns of Antibiotic Prophylaxis in Patients Undergoing Mastectomy-A Survey of Members of the American Society of Breast Surgeons. Sattar, Abida K., Hania Shahzad, Taleaa Masroor, Russell Seth Martins, Nida Zahid, and Farin F. Amersi. Annals of Surgical Oncology, July. 

Expanding the Staging Criteria for T1-2N0 Hormone-Receptor Positive Breast Cancer Patients Enrolled in TAILORx. Kantor, Olga, Harold J. Burstein, Tari A. King, Steven Shak, Christy A. Russell, Armando E. Giuliano, Gabriel N. Hortobagyi, Eric P. Winer, Larissa A. Korde, Joseph A. Sparano, and Elizabeth A. Mittendorf. Annals of Surgical Oncology, July.

Human Fibroblasts Facilitate the Generation of IPSCs-Derived Mammary-like Organoids. Dai, Xueqin, Xinye Wang, Chuanyu Yang, Maobo Huang, Zhongmei Zhou, Ying Qu, Xiaojiang Cui, Rong Liu, and Ceshi Chen. Stem Cell Research & Therapy 13 (1): 377.

Correction: Integration of Metabolites From Meta-Analysis With Transcriptome Reveals Enhanced SPHK1 in PDAC With a Background of Pancreatitis. Ketavarapu, Vijayasarathy, Vishnubhotla Ravikanth, Mitnala Sasikala, G. V. Rao, Ch Venkataramana Devi, Prabhakar Sripadi, Murali Satyanarayana Bethu, Ramars Amanchy, H. V. V. Murthy, Stephen J. Pandol, and D. Nageshwar Reddy. BMC Cancer 22 (1): 825.

HCC EV ECG Score: An Extracellular Vesicle-Based Protein Assay for Detection of Early-Stage Hepatocellular Carcinoma. Sun, Na, Ceng Zhang, Yi-Te Lee, Benjamin V. Tran, Jing Wang, Hyoyong Kim, Junseok Lee, Ryan Y. Zhang, Jasmine J. Wang, Junhui Hu, Zhicheng Zhang, Manaf S. Alsudaney, Yazhen Zhu, et al. Hepatology (Baltimore, Md.), July.

The Driver Role of JAK-STAT Signalling in Cancer Stemness Capabilities Leading to New Therapeutic Strategies for Therapy- and Castration-Resistant Prostate Cancer. Lo, U.-Ging, Yu-An Chen, Junjie Cen, Su Deng, Junghang Luo, Haiyen Zhau, Lin Ho, Chih-Ho Lai, Ping Mu, Leland W. K. Chung, and Jer-Tsong Hsieh. Clinical and Translational Medicine 12 (8): e978.

Discoidin Domain Receptor-Driven Gene Signatures as Markers of Patient Response to Anti-PD-L1 Immune Checkpoint Therapy. You, Sungyong, Minhyung Kim, Xen Ping Hoi, Yu Cheng Lee, Li Wang, David Spetzler, Jim Abraham, Dan Magee, Prerna Jain, Matthew D. Galsky, Keith Syson Chan, and Dan Theodorescu. Journal of the National Cancer Institute, August, djac140.

Therapeutic Value of Sentinel Lymph Node Biopsy in Patients With Melanoma: A Randomized Clinical Trial.Multicenter Selective Lymphadenectomy Trials Study Group, Jessica S. Crystal, John F. Thompson, John Hyngstrom, Corrado Caracò, Jonathan S. Zager, Tiina Jahkola, Tawnya L. Bowles, Elisabetta Pennacchioli, Peter D. Beitsch, Harald J. Hoekstra, Marc Moncrieff, Mark B. Faries, et al. JAMA Surgery, August.

Cardiac Surgery 

Left Atrial Thrombus. Akhmerov, Akbarshakh, and Danny Ramzy. The New England Journal of Medicine 387 (5): e8.


Association between Blood Pressure Classification Defined by the 2017 ACC/AHA Guidelines and Coronary Artery Calcification Progression in an Asymptomatic Adult Population. Won, Ki-Bum, Donghee Han, Su-Yeon Choi, Eun Ju Chun, Sung Hak Park, Hae-Won Han, Jidong Sung, Hae Ok Jung, and Hyuk-Jae Chang. European Heart Journal Open 1 (1): oeab009.

Changes in Vascular Function From Preconception to Postpartum Among Mongolian Women. Enkhmaa, Davaasambuu, Davaasambuu Ganmaa, Lauren J. Tanz, Janet W. Rich-Edwards, Jennifer J. Stuart, Shonkhuuz Enkhtur, Garmaa Gantsetseg, Bandi Batkhishig, Garrett Fitzmaurice, Munkhuu Bayalag, Erdenebileg Nasantogtokh, C. Noel Bairey Merz, and Chrisandra L. Shufelt. Journal of Women’s Health (2002), July.

Cardiac Rehabilitation Performance Predicts 1-Year Major Adverse Cardiovascular Events. Naami, Robert, Edmund Naami, Tamer Omari, Sophia Gordon Lowi, Sharon Shalom Natanzon, Vivek Patel, Addee Lerner, Ehud Rozner, Yoav Turgeman, and Ofir Koren. Clinical Cardiology, July.

Roadmap to a Career in Cardiogenetics. Jones, Xaviar Michael, and Eugenio Cingolani. Heart (British Cardiac Society), July, heartjnl-2021-320692.

Breast Arterial Calcification and Epicardial Adipose Tissue Volume, but Not Density Are Independently Associated With Cardiovascular Risk. Goel, Vinay, Ella Spear, William Cameron, Udit Thakur, Nushrat Sultana, Jasmine Chan, Sean Tan, Mitwa Joshi, Andrew Roberts, Yeong Chee Cheen, Hannah Youn, Damini Dey, Esther Davis, Stephen Nicholls, Adam Brown, and Nitesh Nerlekar. International Journal of Cardiology 360 (August): 78–82.

Durability of Blood Pressure Reduction After Ultrasound Renal Denervation: Three-Year Follow-up of the Treatment Arm of the Randomised RADIANCE-HTN SOLO Trial. Rader, Florian, Ajay J. Kirtane, Yale Wang, Joost Daemen, Philipp Lurz, Jeremy Sayer, Manish Saxena, Terry Levy, Andrea P. Scicli, Lisa Thackeray, Michel Azizi, Michael A. Weber, and Collaborators. EuroIntervention: Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, August, EIJ-D-22-00305.

Computational Biomedicine 

Identifying Genetic Markers Enriched by Brain Imaging Endophenotypes in Alzheimer’s Disease. Kim, Mansu, Ruiming Wu, Xiaohui Yao, Andrew J. Saykin, Jason H. Moore, Li Shen, and Alzheimer’s Disease Neuroimaging Initiative. BMC Medical Genomics 15 (Suppl 2): 168.


Early Versus Late Acute Coronary Syndrome Risk Patterns of Coronary Atherosclerotic Plaque. Hoogen, Inge J. van den, Wijnand J. Stuijfzand, Umberto Gianni, Alexander R. van Rosendael, A. Maxim Bax, Yao Lu, Sara W. Tantawy, Emma J. Hollenberg, Daniele Andreini, Mouaz H. Al-Mallah, Filippo Cademartiri, Kavitha Chinnaiyan, Benjamin J. W. Chow, Edoardo Conte, Ricardo C. Cury, Gudrun Feuchtner, Pedro de Araújo Gonçalves, Martin Hadamitzky, Yong-Jin Kim, Jonathon Leipsic, Erica Maffei, Hugo Marques, Fabian Plank, Gianluca Pontone, Todd C. Villines, Sang-Eun Lee, Subhi J. Al’Aref, Lohendran Baskaran, Ibrahim Danad, Heidi Gransar, Matthew J. Budoff, Habib Samady, Renu Virmani, Daniel S. Berman, Hyuk-Jae Chang, Jagat Narula, James K. Min, Jeroen J. Bax, Fay Y. Lin, Leslee J. Shaw, and ICONIC Investigators. European Heart Journal. Cardiovascular Imaging, July, jeac114.


Whole Genome Sequence Association Analysis of Fasting Glucose and Fasting Insulin Levels in Diverse Cohorts From the NHLBI TOPMed Program. DiCorpo, Daniel, Sheila M. Gaynor, Emily M. Russell, Kenneth E. Westerman, Laura M. Raffield, Timothy D. Majarian, Peitao Wu, Chloé Sarnowski, Heather M. Highland, Anne Jackson, Natalie R. Hasbani, Paul S. de Vries, Alisa K. Manning, et al. Communications Biology 5 (1): 756.

Hospital Diabetes Meeting. Huang, Jingtong, Andrea M. Yeung, Kevin T. Nguyen, Nicole Y. Xu, Jean-Charles Preiser, Robert J. Rushakoff, Jane Jeffrie Seley, Guillermo E. Umpierrez, Amisha Wallia, Andjela T. Drincic, Roma Gianchandani, M. Cecilia Lansang, Umesh Masharani, Nestoras Mathioudakis, Francisco J. Pasquel, Signe Schmidt, Viral N. Shah, Elias K. Spanakis, Andreas Stuhr, Gerlies M. Treiber, and David C. Klonoff. Journal of Diabetes Science and Technology, July, 19322968221110880.

An Assessment of the Value of Donor-Derived Cell-Free DNA Surveillance in Patients With Preserved Kidney Allograft Function. Huang, Edmund, Mark Haas, Matt Gillespie, Supreet Sethi, Alice Peng, Reiad Najjar, Ashley Vo, and Stanley C. Jordan. Transplantation, August.

Differences in Glucose Levels Between Arms Using Continuous Glucose Monitors. Shah, Sachin A., Kevin Pham, Virginia Hon, Jeremy Lim, and Sanjay Kaul. Journal of Diabetes Science and Technology, August, 19322968221116390.


Improving Postoperative Pain Score Among Charcot Marie Tooth Reconstructive Surgery Receiving Ambulatory Nerve Infusion Therapy. Deacon, Ann, Ann Duran, Michael Kissen, and Elliot Schwartz. Journal of PeriAnesthesia Nursing 37 (4): e2–3.

More Than Just a Check-the-Box Form: Informed Consent. Wang, Florence, and Barbara Sheppard. Critical Care Nurse 42 (4): 80–83.


Barriers to Surgical Menopause Counseling in Gynecologic Cancers: A Quantitative and Qualitative Study of Patients and Providers. Wang, Connor C., Dandi S. Huang, Anisa M. Carlson, Zhanhai Li, Ahmed Al-Niaimi, and Makeba Williams. Menopause (New York, N.Y.) 29 (8): 926–31.

Preventing Obesity in Midlife Women: A Recommendation From the Women’s Preventive Services Initiative. Chelmow, David, Kimberly D. Gregory, Catherine Witkop, Susan Hoffstetter, Linda Humphrey, Carla Picardo, James J. Stevermer, Amy G. Cantor, Heidi D. Nelson, Sarah Son, Jeanne A. Conry, Francisco Garcia, Susan M. Kendig, Nancy O’Reilly, Amir Qaseem, Diana Ramos, Alina Salganicoff, Julie K. Wood, Christopher Zahn, and Women’s Preventive Services Initiative*. Annals of Internal Medicine, August.


The Substance Use Treatment and Recovery Team (START) Study: Protocol for a Multi-Site Randomized Controlled Trial Evaluating an Intervention to Improve Initiation of Medication and Linkage to Post-Discharge Care for Hospitalized Patients With Opioid Use Disorder. Ober, Allison J., Cristina Murray-Krezan, Kimberly Page, Peter D. Friedmann, Karen Chan Osilla, Stephen Ryzewicz, Sergio Huerta, Mia W. Mazer, Isabel Leamon, Gabrielle Messineo, Katherine E. Watkins, Teryl Nuckols, and Itai Danovitch. Addiction Science & Clinical Practice 17 (1): 39.

Radiation Oncology 

Over 300 Radiation Caries Papers: Reflections From the Rearview Mirror. Pedroso, Caique Mariano, Cesar Augusto Migliorati, Joel B. Epstein, Ana Carolina Prado Ribeiro, Thaís Bianca Brandão, Márcio Ajudarte Lopes, Mário Fernando de Goes, and Alan Roger Santos-Silva. Frontiers in Oral Health 3: 961594.

Synergistic Effects of Radiotherapy and Targeted Immunotherapy in Improving Tumor Treatment Efficacy: A Review. Dar, Tahir Bashir, Fleury Augustin Nsole Biteghe, Ruchi Kakar-Bhanot, Eric Chekwebe Aniogo, Zaria Malindi, Olusiji Alex Akinrinmade, Nyangone Ekome Toung Chalomie, Arnaud John Kombe Kombe, Sophie Aboughe Angone, Jean Marc Ngome Ndong, and Jean Delacroix Ndong. Clinical & Translational Oncology, August.


Jaw-in-a-Riley-Day: Mandibular Free Flap Reconstruction With Virtual Surgical Planning in a Patient With Familial Dysautonomia. Itamura, Kyohei, Steven Kupferman, Jay Lee, and Jon Mallen-St Clair. Cureus 14 (6): e26336.

Exophytic Laryngeal Mass. Landsberger, Hannah, Gene C. Liu, and Anca M. Barbu. JAMA Otolaryngology-- Head & Neck Surgery, July.

Comparison of Permanent Hair Removal Procedures Before Gender-Affirming Vaginoplasty: Why We Should Consider Laser Hair Removal as a First-Line Treatment for Patients Who Meet Criteria. Yuan, Nance, Alexandra Terris Feldman, Patrick Chin, Michael Zaliznyak, Susan Rabizadeh, and Maurice M. Garcia. Sexual Medicine10 (5): 100545.

Correcting Coagulopathy With Fresh Frozen Plasma in the Surgical Intensive Care Unit: How Much Do We Need to Transfuse? Hashim, Yassar M., Navpreet K. Dhillon, Nicholas P. Rottler, Joshua Ghoulian, Galinos Barmparas, and Eric J. Ley. The American Surgeon 88 (8): 2030–34.

Evaluating the Incidence and Predictors of Anti-NMDAR Encephalitis in a Contemporary Cohort of Patients Diagnosed With Dermoid Tumors: A National Inpatient Sample Analysis. Shahrestani, Shane, Nolan J. Brown, Rohin Singh, Joshua S. Kurtz, Neal A. Patel, Alexander S. Himstead, Tasha Nasrollahi, Michela Borrelli, Noah Pierzchajlo, Seth C. Ransom, and Julian Gendreau. Journal of Clinical Neuroscience 102 (August): 109–13.

Validation of an Artificial Intelligence Platform for the Guidance of Safe Laparoscopic Cholecystectomy. Laplante, Simon, Babak Namazi, Parmiss Kiani, Daniel A. Hashimoto, Adnan Alseidi, Mauricio Pasten, L. Michael Brunt, Sujata Gill, Brian Davis, Matthew Bloom, Luise Pernar, Allan Okrainec, and Amin Madani. Surgical Endoscopy, August.

Free Tissue Transfer for Skull Base Osteoradionecrosis: A Novel Approach in the Endoscopic Era. Sreenath, Satyan B., Kevin T. Grafmiller, Dennis M. Tang, Scott A. Roof, Troy D. Woodard, Varun R. Kshettry, Pablo F. Recinos, Raj Sindwani, and Michael A. Fritz. The Laryngoscope, August.