Faculty Publications: July 14-21

This week’s edition of Faculty Publications includes Cedars-Sinai studies that were published July 14-21. If you have a published paper from this period that does not appear on this list, please contact Sue Marone, who will add it to next week’s collection.

Biomedical Sciences 

Lactococcus Lactis Subsp. Cremoris C60 Induces Macrophages Activation That Enhances CD4+ T Cell-Based Adaptive Immunity. Saito, Suguru, Alato Okuno, Nanae Kakizaki, Toshio Maekawa, and Noriko M. Tsuji. Bioscience of Microbiota, Food and Health 41 (3): 130–36.

TCR-Vγδ Usage Distinguishes Protumor From Antitumor Intestinal Γδ T Cell Subsets. Reis, Bernardo S., Patrick W. Darcy, Iasha Z. Khan, Christine S. Moon, Adam E. Kornberg, Vanessa S. Schneider, Yelina Alvarez, Olawale Eleso, Caixia Zhu, Marina Schernthanner, Ainsley Lockhart, Aubrey Reed, Juliana Bortolatto, Tiago B. R. Castro, Angelina M. Bilate, Sergei Grivennikov, Arnold S. Han, and Daniel Mucida. Science (New York, N.Y.) 377 (6603): 276–84.

Cancer

TOP1 Inhibition Induces Bifurcated JNK/MYC Signaling That Dictates Cancer Cell Sensitivity. Liu, Qizhi, Stacey Chung, Michael M. Murata, Bingchen Han, Bowen Gao, Maoqi Zhang, Tian-Yu Lee, Evgeny Chirshev, Juli Unternaehrer, Hisashi Tanaka, Armando E. Giuliano, Yukun Cui, and Xiaojiang Cui. International Journal of Biological Sciences 18 (10): 4203–18.

Immunotherapy in Synchronous MSI-H Rectal Adenocarcinoma and Upper Tract Urothelial Carcinoma: A Case Report. Hsieh-Wong, Jacqueline, James Liu, Jasmine Huynh, Mamta Parikh, Edward Kim, Jun Gong, Wissam Halabi, Mamatha Siricilla, Anupam Mitra, Kyra Toomey, and May Cho. Journal of Gastrointestinal Oncology 13 (3): 1473–80.

Third CMAS (CytoJournal Monograph/Atlas Series) Titled ‘Uterine Cervix Cancer and The Bethesda System.’ Shidham, Vinod B., Shikha Bose, Zubair Wahid Baloch, Meherbano Mustafa Kamal, Jasvinder Kaur Bhatia, and Lester J. Layfield. Cytojournal 19 (July).

PAI-1 Is a Potential Transcriptional Silencer That Supports Bladder Cancer Cell Activity. Furuya, Hideki, Yuka Sasaki, Runpu Chen, Rafael Peres, Kanani Hokutan, Kaoru Murakami, Nari Kim, Owen T. M. Chan, Ian Pagano, Lars Dyrskjøt, Jørgen B. Jensen, Per-Uno Malmstrom, Ulrika Segersten, Yijun Sun, Abolfazl Arab, Hani Goodarzi, Steve Goodison, and Charles J. Rosser. Scientific Reports 12 (1): 12186.

Advance Care Planning in Patients With Metastatic Cancer: A Quality Improvement Initiative. Oppenheim, Steven, Robert A. Figlin, Edward G. Seferian, Margaret Reed, Scott A. Irwin, and Bradley T. Rosen. JCO Oncology Practice, July, OP2200160.

Chemical Exchange Saturation Transfer for Pancreatic Ductal Adenocarcinoma Evaluation. Wang, Lixia, Zhengwei Zhou, Srinivas Gaddam, Nan Wang, Yibin Xie, Zixin Deng, Zhaoyang Fan, Anthony G. Christodoulou, Fei Han, Simon K. Lo, Ashley M. Wachsman, Andrew E. Hendifar, Tao Jiang, Stephen J. Pandol, and Debiao Li. Pancreas, July.

Cardiac Surgery 

Increased Opportunities for Transplantation for Women in the New Heart Allocation System. Defilippis, Ersilia M., Lauren K. Truby, Kevin J. Clerkin, Elena Donald, Lauren Sinnenberg, Anubodh S. Varshney, Rebecca Cogswell, Michelle M. Kittleson, Jennifer H. Haythe, Michael M. Givertz, Eileen M. Hsich, Richa Agarwal, Veli K. Topkara, and Maryjane Farr. Journal of Cardiac Failure 28 (7): 1149–57.

Previous Cardiac Surgery in Acute Type A Aortic Dissection Repair - Not a Contraindication, But Proceed With Caution. Chen, Qiudong, and Michael E. Bowdish. The Annals of Thoracic Surgery, July, S0003-4975(22)00961-4.

Heart Transplantation After Total Artificial Heart Bridging - Outcomes over 15 Years. Chen, Qiudong, Joshua Chan, Akbarshakh Akhmerov, Amy Roach, Dominic Emerson, Dominick Megna, Pedro Catarino, Jaime Moriguchi, David Chang, Michelle Kittleson, Dael Geft, Jon Kobashigawa, Joanna Chikwe, and Fardad Esmailian. Clinical Transplantation, July, e14781.

Evolving Trends and Widening Racial Disparities in Children Listed for Heart Transplantation in the United States. Zubair, M. Mujeeb, Qiudong Chen, Georgina Rowe, George Gill, Jason Thomas, Shrishiv A. Timbalia, Asishana A. Osho, Michael E. Bowdish, Vikram Sood, Kurt R. Schumacher, Joanna Chikwe, and Richard W. Kim. Circulation 146 (3): 262–64.

Cardiology

Reduced Myocardial Perfusion Is Common Among Subjects With Ischemia and No Obstructive Coronary Artery Disease and Heart Failure With Preserved Ejection Fraction: A Report From the WISE-CVD Continuation Study. Aldiwani, Haider, Michael D. Nelson, Behzad Sharif, Janet Wei, T. Jake Samuel, Nissi Suppogu, Odayme Quesada, Galen Cook-Wiens, Edward Gill, Lidia S. Szczepaniak, Louise E. J. Thomson, Balaji Tamarappoo, Anum Asif, Chrisandra Shufelt, Daniel Berman, and C. Noel Bairey Merz. Vessel Plus 6: 16.

Mortality Risk in Takotsubo Syndrome Versus Myocarditis. Kwan, Alan C., Jesse Navarrette, Patrick Botting, Melanie T. Chen, Janet Wei, C. Noel Bairey Merz, Joseph E. Ebinger, and Susan Cheng. Journal of the American Heart Association, June, e025191.

Quantitative Plaque Analysis With A.I.-Augmented CCTA in End-Stage Renal Disease and Complex CAD. Cho, Geoffrey W., Ahmed K. Ghanem, Carlos G. Quesada, Tami R. Crabtree, Robert S. Jennings, Matthew J. Budoff, Andrew D. Choi, James K. Min, Ronald P. Karlsberg, and James P. Earls. Clinical Imaging89 (July): 155–61.

Racial and Ethnic Disparities in Arrhythmia Care: A Call for Action. Thomas, Kevin L., Jalaj Garg, Poonam Velagapudi, Rakesh Gopinathannair, Mina K. Chung, Fred Kusumoto, Olujimi Ajijola, Larry R. Jackson, Mohit K. Turagam, Jose A. Joglar, Felix O. Sogade, John M. Fontaine, Andrew D. Krahn, Andrea M. Russo, Christine Albert, and Dhanunjaya R. Lakkireddy. Heart Rhythm, July, S1547-5271(22)02051-3.

Harnessing the Benefits of Yoga for Myositis, Muscle Dystrophies, and Other Musculoskeletal Disorders. Saud, Ahmad, Maryam Abbasi, Holly Merris, Pranav Parth, Xaviar Michael Jones, Rohit Aggarwal, and Latika Gupta. Clinical Rheumatology, July.

Acute Myocardial Infarction and Concomitant Acute Intracranial Hemorrhage: Clinical Characteristics and Outcomes. Cao, Xiangqi, Meng Wei, Manyun Tang, Zhijie Jian, Hui Liu, Xin Yue, Guogang Luo, Chaofeng Sun, and Fengwei Guo. Journal of Investigative Medicine, July, jim-2022-002334.

Review of Immunologic Manifestations of COVID-19 Infection and Vaccination. Pozdnyakova, Valeriya, Brittany Weber, Susan Cheng, and Joseph E. Ebinger. Cardiology Clinics 40 (3): 301–8.

Computational Biomedicine 

Novel Digital Approaches to the Assessment of Problematic Opioid Use. Freda, Philip J., Henry R. Kranzler, and Jason H. Moore. BioData Mining 15 (1): 14.

Imaging

Discordance Between Coronary Artery Calcium Area and Density Predicts Long-Term Atherosclerotic Cardiovascular Disease Risk. Razavi, Alexander C., Marly van Assen, Carlo N. De Cecco, Zeina A. Dardari, Daniel S. Berman, Matthew J. Budoff, Michael D. Miedema, Khurram Nasir, Alan Rozanski, John A. Rumberger, Leslee J. Shaw, Laurence S. Sperling, Seamus P. Whelton, Martin Bødtker Mortensen, Michael J. Blaha, and Omar Dzaye. JACC. Cardiovascular Imaging, July, S1936-878X(22)00396-5.

Medicine

Human Milk Oligosaccharides Impact Cellular and Inflammatory Gene Expression and Immune Response. Rosa, Fernanda, Ashok K. Sharma, Manoj Gurung, David Casero, Katelin Matazel, Lars Bode, Christy Simecka, Ahmed A. Elolimy, Patricia Tripp, Christopher Randolph, Timothy W. Hand, Keith D. Williams, Tanya LeRoith, and Laxmi Yeruva. Frontiers in Immunology 13: 907529.

Serum Glial Cell Line-Derived Neurotrophic Factor (SGDNF) Is a Novel Biomarker in Predicting Cirrhosis in Patients With Chronic Hepatitis B. Yang, Guangyue, Liping Zhuang, Tiantian Sun, Yee Hui Yeo, Le Tao, Wei Zhang, Wenting Ma, Liu Wu, Zongguo Yang, Yanqin Yang, Dongying Xue, Jie Zhang, Rilu Feng, Ebert Matthias P, Steven Dooley, Ekihiro Seki, Ping Liu, and Cheng Liu. Canadian Journal of Gastroenterology & Hepatology 2022: 1048104.

Elafin Reverses Intestinal Fibrosis by Inhibiting Cathepsin S-Mediated Protease-Activated Receptor 2. Xie, Ying, Lindsey Fontenot, Andrea Chupina Estrada, Becca Nelson, Jiani Wang, David Q. Shih, Wendy Ho, S. Anjani Mattai, Florian Rieder, Dane D. Jensen, Nigel W. Bunnett, and Hon Wai Koon. Cellular and Molecular Gastroenterology and Hepatology, July, S2352-345X(22)00157-6.

Protein Kinase D: A Therapeutic Target in Experimental Alcoholic Pancreatitis. Yuan, Jingzhen, Chintan Chheda, Grace Tan, Omer Elmadbouh, and Stephen J. Pandol. Biochimica Et Biophysica Acta. Molecular Basis of Disease 1868 (11): 166486.

AGA Clinical Practice Update: Diagnosis and Management of Nonalcoholic Fatty Liver Disease in Lean Individuals: Expert Review. Long, Michelle T., Mazen Noureddin, and Joseph K. Lim. Gastroenterology, July, S0016-5085(22)00628-X.

Diminished T-Cell Immune Responses to SARS-CoV-2 Omicron Variant After BNT162b2 Vaccination. Jordan, Stanley C., Bong-Ha Shin, Edgar Rodriguez, Vo Ashley, null NorikoAmmerman, and Ruan Zhang. Immunology Letters, July, S0165-2478(22)00102-X.

Author Correction: Transcriptional Regulation of N6-Methyladenosine Orchestrates Sex-Dimorphic Metabolic Traits. Salisbury, David A., David Casero, Zhengyi Zhang, Dan Wang, Jason Kim, Xiaohui Wu, Laurent Vergnes, Aashiq H. Mirza, Paola Leon-Mimila, Kevin J. Williams, Adriana Huertas-Vazquez, Samie R. Jaffrey, Karen Reue, Jianjun Chen, and Tamer Sallam. Nature Metabolism, July.

Integration of Metabolites From Meta-Analysis With Transcriptome Reveals Enhanced SPHK1 in PDAC With a Background of Pancreatitis. Ketavarapu, Vijayasarathy, Vishnubhotla Ravikanth, Mitnala Sasikala, G. V. Rao, Ch Venkataramana Devi, Prabhakar Sripadi, Murali Satyanarayana Bethu, Ramars Amanchy, H. V. V. Murthy, Stephen J. Pandol, and D. Nageshwar Reddy. BMC Cancer 22 (1): 792.

T1 Signal Intensity Ratio of the Pancreas as an Imaging Biomarker for the Staging of Chronic Pancreatitis. Tirkes, Temel, Anil K. Dasyam, Zarine K. Shah, Evan L. Fogel, Santhi Swaroop Vege, Liang Li, Shuang Li, Stephanie T. Chang, Carlos A. Farinas, Joseph R. Grajo, Kareem Mawad, Naoki Takahashi, Sudhakar K. Venkatesh, Ashley Wachsman, William E. Fisher, Christopher E. Forsmark, Phil A. Hart, Stephen J. Pandol, Walter G. Park, Stephen K. Van Den Eeden, Yunlong Yang, Mark Topazian, Dana K. Andersen, Jose Serrano, Darwin L. Conwell, Dhiraj Yadav, and Consortium for the Study of Chronic Pancreatitis, Diabetes, Pancreatic Cancer (CPDPC). Abdominal Radiology (New York), July.

Chemical Optimization of SiRNA for Safe and Efficient Silencing of Placental SFLT1. Davis, Sarah M., Vignesh N. Hariharan, Agnes Lo, Anton A. Turanov, Dimas Echeverria, Jacquelyn Sousa, Nicholas McHugh, Annabelle Biscans, Julia F. Alterman, S. Ananth Karumanchi, Melissa J. Moore, and Anastasia Khvorova. Molecular Therapy. Nucleic Acids 29 (September): 135–49.

Neurology

Neural Correlates of Risky Decision Making in Parkinson’s Disease Patients With Impulse Control Disorders. Ruitenberg, Marit F. L., Vincent Koppelmans, Tina Wu, Bruno B. Averbeck, Kelvin L. Chou, and Rachael D. Seidler. Experimental Brain Research, July.

Neurosurgery

Extensive Spontaneous Cervical Epidural Hematoma Due to Oral Anticoagulant (Dabigatran) Successfully Treated With Reversal Agent Idarucizumab Alone. Uddin, Syed-Abdullah, Katerina Roma, Lindsey Ross, George Hanna, Doniel Drazin, and Terrence T. Kim. Surgical Neurology International 13: 259.

Letter: Commentary: Cost-Effectiveness Analysis of Encephaloduroarteriosynangiosis Surgery for Symptomatic Intracranial Atherosclerotic Disease. Gonzalez, Nestor R., and Miguel D. Quintero-Consuegra. Neurosurgery 91 (2): e74–75.

OBGYN

Reconsidering Absolute Diagnostic Thresholds in Intrahepatic Cholestasis of Pregnancy. Tamzali, Ines, Michael L. Pirics, Matthew Biocca, and Richard M. Burwick. American Journal of Obstetrics and Gynecology, July, S0002-9378(22)00542-7.

Orthopaedics

Amyloid Deposition: An Unusual Case of Deep Gluteal Syndrome and Sciatic Nerve Compression: A Case Report. Parikh, Harin B., George R. Matcuk, Matthew Leong, Mark S. Vrahas, and Mitchel Seruya. JBJS Case Connector 12 (3).

An Initial Injection and a Crossover Injection of Amniotic Suspension Allograft Following Failed Treatment With Hyaluronic Acid or Saline Are Equally Effective in the Treatment of Moderate Symptomatic Knee Osteoarthritis Over 12 Months. Gomoll, Andreas H., Bert R. Mandelbaum, Jack Farr, W. Tad Archambault, Seth L. Sherman, Samuel K. Tabet, Kelly A. Kimmerling, and Katie C. Mowry. Arthroscopy: The Journal of Arthroscopic & Related Surgery, July, S0749-8063(22)00411-X.

Trends in Health Care Expenditures and Patient Out-of-Pocket Expenses in Primary Anterior Cruciate Ligament Reconstruction. Carbone, Andrew D., Kevin Wang, Justin Tiao, Brennan Chu, Jashvant Poeran, Alexis C. Colvin, James N. Gladstone, and Shawn G. Anthony. The American Journal of Sports Medicine, July, 3635465221107082.

Rehabilitation Medicine

Family Communication Challenges of Adolescents and Young Adults With Li-Fraumeni Syndrome: Implications for Psychosocial Care. Rising, Camella J., Catherine Wilsnack, Patrick Boyd, Alix G. Sleight, Sadie P. Hutson, Payal P. Khincha, and Allison Werner-Lin. Patient Education and Counseling, July.

Surgery

A Theranostic 3D Ultrasound Imaging System for High Resolution Image-Guided Therapy. Bendjador, Hanna, Josquin Foiret, Robert Wodnicki, Douglas N. Stephens, Zoe Krut, Eun-Yeong Park, Zulma Gazit, Dan Gazit, Gadi Pelled, and Katherine W. Ferrara. Theranostics 12 (11): 4949–64.

Cochlear Implantation Performance Outcomes in Patients over 80 Years Old. Wichova, Helena, Dawna Mills, Sarah Beatty, Kevin Peng, and Mia Miller. Laryngoscope Investigative Otolaryngology 7 (3): 847–53.